WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2012049874) BIOMARKER FOR DIAGNOSIS OF FATTY LIVER DISEASES, METHOD FOR MEASURING SAME, COMPUTER PROGRAM AND STORAGE MEDIUM
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/049874    International Application No.:    PCT/JP2011/059813
Publication Date: 19.04.2012 International Filing Date: 21.04.2011
IPC:
G01N 33/68 (2006.01), G01N 27/62 (2006.01), G01N 33/15 (2006.01), G01N 33/50 (2006.01), G01N 33/74 (2006.01), G01N 33/92 (2006.01), A01K 67/027 (2006.01)
Applicants: HUMAN METABOLOME TECHNOLOGIES, INC. [JP/JP]; 246-2, Aza Mizukami, Kakuganji, Tsuruoka-shi, Yamagata 9970052 (JP) (For All Designated States Except US).
TOKYO WOMEN'S MEDICAL UNIVERSITY [JP/JP]; 8-1, Kawada-cho, Shinjuku-ku, Tokyo 1628666 (JP) (For All Designated States Except US).
HASHIMOTO, Etsuko [JP/JP]; (JP) (For US Only).
TOKUSHIGE, Katsutoshi [JP/JP]; (JP) (For US Only).
OHGA, Takushi [JP/JP]; (JP) (For US Only).
OHASHI, Yoshiaki [JP/JP]; (JP) (For US Only).
SASAKI, Kazunori [JP/JP]; (JP) (For US Only)
Inventors: HASHIMOTO, Etsuko; (JP).
TOKUSHIGE, Katsutoshi; (JP).
OHGA, Takushi; (JP).
OHASHI, Yoshiaki; (JP).
SASAKI, Kazunori; (JP)
Agent: ISSHIKI & CO.; Rookin-Shinbashi Bldg., 12-7, Shinbashi 2-chome, Minato-ku, Tokyo 1050004 (JP)
Priority Data:
2010-230469 13.10.2010 JP
Title (EN) BIOMARKER FOR DIAGNOSIS OF FATTY LIVER DISEASES, METHOD FOR MEASURING SAME, COMPUTER PROGRAM AND STORAGE MEDIUM
(FR) BIOMARQUEUR POUR LE DIAGNOSTIC DE STÉATOSES HÉPATIQUES, PROCÉDÉ DE MESURE CORRESPONDANT, PROGRAMME D'ORDINATEUR ET SUPPORT DE STOCKAGE ASSOCIÉS
(JA) 脂肪性肝疾患を診断するためのバイオマーカー、その測定方法、コンピュータプログラム、および、記憶媒体
Abstract: front page image
(EN)[Problem] To provide a biomarker for the diagnosis of fatty liver diseases. [Solution] One or more compounds selected from the group consisting of etiocholanolone 3-sulfate, nervonic acid, α-tocopherol, 16-hydroxydehydroepiandrosterone 3-sulfate, dehydroepiandrosterone 2-sulfate, taurine, 15-hydroxyeicosatetraenoic acid, serotonin and thyroxine are used as biomarkers for the diagnosis, and fatty liver diseases are diagnosed by measuring the amounts of the compounds contained in a blood sample taken.
(FR)L'invention a pour but de fournir un biomarqueur pour le diagnostic de stéatoses hépatiques. A cet effet, un ou plusieurs composés choisis dans le groupe consistant en 3-sulfate d'étiocholanolone, acide nervonique, l'α-tocophérol, 3-sulfate de 16-hydroxydéhydroépiandrostérone, 2-sulfate de déhydroépiandrostérone, taurine, acide 15-hydroxyéicosatétraénoïque, sérotonine et thyroxine sont utilisés en tant que biomarqueurs pour le diagnostic, et des stéatoses hépatiques sont diagnostiquées par mesure des quantités de composés contenus dans un échantillon sanguin prélevé.
(JA)【課題】脂肪性肝疾患を診断するためのバイオマーカーを提供すること。 【解決手段】エチオコラノロン3-硫酸、ネルボン酸、α-トコフェロール、16-ヒドロキシデヒドロエピアンドロステロン3-硫酸、デヒドロエピアンドロステロン-2硫酸、タウリン、15-ヒドロキシエイコサテトラエン酸、セロトニンおよびチロキシンからなる群から選択される一以上の化合物を、診断するためのバイオマーカーとし、採取した血液中の含有量を測定することによって、脂肪性肝疾患を診断する。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)