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Pub. No.:    WO/2012/049317    International Application No.:    PCT/EP2011/068040
Publication Date: 19.04.2012 International Filing Date: 14.10.2011
A61K 39/245 (2006.01), C07K 14/045 (2006.01)
Applicants: GLAXOSMITHKLINE BIOLOGICALS S.A. [BE/BE]; rue de l'Institut 89 B-1330 Rixensart (BE) (For All Designated States Except US).
BAUDOUX, Guy, Jean, Marie, Fernand, Pierre [BE/BE]; (BE) (For US Only).
BLAIS, Normand [CA/CA]; (CA) (For US Only).
MARCHAND, Martine [BE/BE]; (BE) (For US Only)
Inventors: BAUDOUX, Guy, Jean, Marie, Fernand, Pierre; (BE).
BLAIS, Normand; (CA).
MARCHAND, Martine; (BE)
Agent: VAN DEN HAZEL, Hendrik, Bart; GlaxoSmithKline Global Patents CN925.1 980 Great West Road Brentford Middlesex TW8 9GS (GB)
Priority Data:
61/393,413 15.10.2010 US
Abstract: front page image
(EN)The invention relates to a cytomegalovirus (CMV) gB polypeptide comprising at least a portion of a gB protein extracellular domain comprising a fusion loop 1 (FL1) domain and a fusion loop 2 (FL2) domain, wherein at least one of the FL1 and FL2 domains comprises at least one amino acid deletion or substitution.
(FR)L'invention concerne un polypeptide gB de cytomégalovirus (CMV) comprenant au moins une partie d'un domaine extracellulaire de protéine gB comprenant un domaine de boucle de fusion 1 (FL1) et un domaine de boucle de fusion 2 (FL2), au moins un des domaines FL1 et FL2 comprenant au moins une délétion ou une substitution d'acide aminé.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)