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Machine translation
1. (WO2012048854) FORMULATION SUITABLE FOR STABILIZING PROTEINS, WHICH IS FREE OF MAMMALIAN EXCIPIENTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/048854    International Application No.:    PCT/EP2011/005088
Publication Date: 19.04.2012 International Filing Date: 11.10.2011
IPC:
A61K 9/19 (2006.01), A61K 47/14 (2006.01), A61K 47/26 (2006.01), A61K 47/32 (2006.01), A61K 47/36 (2006.01)
Applicants: MERZ PHARMA GMBH & CO. KGaA [DE/DE]; Eckenheimer Landstraße 100 60318 Frankfurt am Main (DE) (For All Designated States Except US).
TAYLOR, Harold [US/DE]; (DE) (For US Only).
MANDER, Gerd J. [DE/DE]; (DE) (For US Only).
BURGER, Markus [DE/DE]; (DE) (For US Only)
Inventors: TAYLOR, Harold; (DE).
MANDER, Gerd J.; (DE).
BURGER, Markus; (DE)
Agent: RICKER, Mathias; Wallinger Ricker Schlotter Foerstl Patent- und Rechtsanwälte Zweibrückenstrasse 5-7 80331 München (DE)
Priority Data:
10013567.2 12.10.2010 EP
61/404,915 12.10.2010 US
Title (EN) FORMULATION SUITABLE FOR STABILIZING PROTEINS, WHICH IS FREE OF MAMMALIAN EXCIPIENTS
(FR) PRÉPARATION STABILISATRICE DE PROTÉINES ET EXEMPTE D'EXCIPIENTS D'ORIGINE MAMMIFÈRE
Abstract: front page image
(EN)A formulation free of protein which stabilizes pharmaceutical active proteins, peptides, or mixtures thereof in large scale production processes comprising a mixture of a hydrophilic polymer and a non-ionic detergent, and a mixture of a polyalcohol and a sugar. In some embodiments the polyalcohol is absent.
(FR)Cette invention concerne une préparation dépourvue de protéine et qui stabilise les protéines et les peptides pharmaceutiques actifs, ou leurs mélanges, dans des procédés de production à grande échelle comprenant un mélange constitué d'un polymère hydrophile et d'un détergent non ionique, et un mélange constitué d'un polyol et d'un sucre. Dans certains modes de réalisation, le polyol n'est pas présent.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)