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Machine translation
1. (WO2012048165) INJECTABLE, PORE-FORMING HYDROGELS FOR MATERIALS-BASED CELL THERAPIES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/048165    International Application No.:    PCT/US2011/055174
Publication Date: 12.04.2012 International Filing Date: 06.10.2011
IPC:
A61L 27/52 (2006.01), A61L 27/54 (2006.01), A61L 27/38 (2006.01), C12N 5/0775 (2010.01), A61L 27/56 (2006.01), A61L 27/22 (2006.01)
Applicants: PRESIDENT AND FELLOWS OF HARVARD COLLEGE [US/US]; 17 Quincy Street Cambridge, MA 02138 (US) (For All Designated States Except US).
HUEBSCH, Nathaniel, D. [US/US]; (US) (For US Only).
MADL, Christopher, M. [US/US]; (US) (For US Only).
LEE, Kangwon [KR/US]; (US) (For US Only).
XU, Maria M. [US/US]; (US) (For US Only).
MOONEY, David, J. [US/US]; (US) (For US Only)
Inventors: HUEBSCH, Nathaniel, D.; (US).
MADL, Christopher, M.; (US).
LEE, Kangwon; (US).
XU, Maria M.; (US).
MOONEY, David, J.; (US)
Agent: BEATTIE, Ingrid, A.; Mintz Levin Cohn Ferris Glovsky And Popeo, P.C. One Financial Center Boston, MA 02111 (US)
Priority Data:
61/390,594 06.10.2010 US
Title (EN) INJECTABLE, PORE-FORMING HYDROGELS FOR MATERIALS-BASED CELL THERAPIES
(FR) HYDROGELS INJECTABLE, GÉLIFIANTS POUR DES THÉRAPIES CELLULAIRES À BASE DE MATÉRIAUX
Abstract: front page image
(EN)The invention provides compositions and methods to form pores in situ within hydrogels following hydrogel injection. Pores formed in situ via degradation of sacrificial porogens within the surrounding hydrogel facilitate recruitment or release of cells. Disclosed herein is a material that is not initially porous, but which becomes macroporous over time.
(FR)L'invention concerne des compositions et des procédés pour former des pores in situ dans des hydrogels après injection d'hydrogel. Les pores formés in situ par dégradation de porogènes sacrificiels dans l'hydrogel environnant facilitent le recrutement ou la libération de cellules. La présente invention concerne un matériau qui n'est pas initialement poreux, mais qui devient macroporeux au cours du temps.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)