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1. (WO2012047674) METHODS AND COMPOSITIONS FOR DISEASE TREATMENT USING INHALATION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/047674    International Application No.:    PCT/US2011/053513
Publication Date: 12.04.2012 International Filing Date: 27.09.2011
IPC:
A61P 11/00 (2006.01)
Applicants: MICRODOSE THERAPEUTX, INC. [US/US]; 4262 US Route 1 Monmouth Junction, New Jersey 08852 (US) (For All Designated States Except US).
BYRON, David, A. [US/US]; (US) (For US Only).
WATTS, Alan, B. [US/US]; (US) (For US Only).
COOK, Robert, O. [GB/US]; (US) (For US Only).
AYDIN, Murat [US/US]; (US) (For US Only)
Inventors: BYRON, David, A.; (US).
WATTS, Alan, B.; (US).
COOK, Robert, O.; (US).
AYDIN, Murat; (US)
Agent: SOLOWAY, Norman, P.; Hayes Soloway P.C. 4640 E. Skyline Drive Tucson, Arizona 85718 (US)
Priority Data:
61/386,733 27.09.2010 US
61/386,767 27.09.2010 US
61/386,771 27.09.2010 US
61/386,776 27.09.2010 US
Title (EN) METHODS AND COMPOSITIONS FOR DISEASE TREATMENT USING INHALATION
(FR) PROCÉDÉS ET COMPOSITIONS POUR LE TRAITEMENT DE MALADIE EN UTILISANT L'INHALATION
Abstract: front page image
(EN)Methods and compositions for the treatment of pulmonary disease using inhalation are provided. In particular, the present disclosure provides novel methods and compositions for treating pulmonary diseases such as asthma, bronchitis, COPD, emphysema, lung cancer, pneumonia and pulmonary edema. In addition, the present disclosure provides novel methods and compositions for treating complications associated with pulmonary disease such as corticosteroid resistance and pulmonary tissue destruction. The compositions of the present disclosure comprise corticosteroid resistance agents including but not limited to vitamin D, calcitriol and equivalents thereof. The compositions of the present disclosure also comprise alveolar development and maintenance agents including but not limited to vitamin A, ATRA and equivalents thereof. The present invention provides effective administration of therapeutic agents to specific airways of the lungs by utilizing controlled site delivery.
(FR)La présente invention concerne des procédés et des compositions pour le traitement d'une maladie pulmonaire en utilisant l'inhalation. En particulier, la présente description concerne de nouveaux procédés et compositions pour traiter des maladies pulmonaires telles que l'asthme, la bronchite, la BPCO, l'emphysème, le cancer du poumon, la pneumonie et l'œdème pulmonaire. De plus, la présente description concerne de nouveaux procédés et compositions pour traiter des complications associées à une maladie pulmonaire telle que la résistance aux corticostéroïdes et la destruction de tissu pulmonaire. Les compositions de la présente description comprennent des agents de résistance aux corticostéroïdes comprenant mais non limitées à la vitamine D, le calcitriol et des équivalents de ceux-ci. Les compositions de la présente description comprennent en outre des agents de développement et de maintenance alvéolaire comprenant, mais non limités à, la vitamine A, ATRA et des équivalents de ceux-ci. La présente invention concerne l'administration efficace d'agents thérapeutiques à des voies respiratoires spécifiques des poumons en utilisant l'administration à un site contrôlé.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)