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1. (WO2012047629) SELECTIVE REMOVAL OF AGE-MODIFIED CELLS FOR TREATMENT OF ATHER0SCLEROSIS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/047629    International Application No.:    PCT/US2011/053399
Publication Date: 12.04.2012 International Filing Date: 27.09.2011
IPC:
A61K 41/00 (2006.01), A61K 39/395 (2006.01), A61P 9/10 (2006.01)
Applicants: SIWA CORPORATION [US/US]; 400 East Randolph #3913 Chicago, IL 60601 (US) (For All Designated States Except US).
GRUBER, Lewis [US/US]; (US) (For US Only)
Inventors: GRUBER, Lewis; (US)
Agent: RAUCH, Paul, E.; Evan Law Group Llc 600 West Jackson Blvd. Suite 625 Chicago, IL 60661 (US)
Priority Data:
61/386,932 27.09.2010 US
Title (EN) SELECTIVE REMOVAL OF AGE-MODIFIED CELLS FOR TREATMENT OF ATHER0SCLEROSIS
(FR) ÉLIMINATION SÉLECTIVE DE CELLULES MODIFIÉES PAR AGE POUR LE TRAITEMENT DE L'ATHÉROSCLÉROSE
Abstract: front page image
(EN)A method of treating atherosclerosis comprises removing AGE-modified cells from a patient. The AGE-modified cells include erythrocytes, intima cells, endothelial cells, smooth muscle cells, macrophages, and foam cells. A variety of techniques, such as ultrasound and binding with an anti-AGE antibody, may be used to identify and remove the AGE-modified cells.
(FR)L'invention concerne un procédé de traitement de l'athérosclérose qui comprend l'élimination de cellules modifiées par AGE d'un patient. Les cellules modifiées par AGE comprennent des érythrocytes, des cellules de l'intima, des cellules endothéliales, des cellules des muscles lisses, des macrophages et des cellules spumeuses. Diverses techniques, telles que les ultrasons et la liaison avec un anticorps anti-AGE, peuvent être utilisées pour identifier et éliminer les cellules modifiées par AGE.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)