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1. (WO2012047570) FUSED TRICYCLIC INHIBITORS OF MAMMALIAN TARGET OF RAPAMYCIN
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/047570    International Application No.:    PCT/US2011/053201
Publication Date: 12.04.2012 International Filing Date: 26.09.2011
IPC:
C07D 471/00 (2006.01)
Applicants: MERCK SHARP & DOHME CORP. [US/US]; 126 East Lincoln Avenue Rahway, New Jersey 07065-0907 (US) (For All Designated States Except US).
MENG, Zhaoyang [CN/US]; (US) (For US Only).
REDDY, Panduranga Adulla P. [US/US]; (US) (For US Only).
SIDDIQUI, M. Arshad [CA/US]; (US) (For US Only)
Inventors: MENG, Zhaoyang; (US).
REDDY, Panduranga Adulla P.; (US).
SIDDIQUI, M. Arshad; (US)
Agent: SU, Li; Merck Sharp & Dohme Corp. 126 East Lincoln Avenue Rahway, New Jersey 07065-0907 (US)
Priority Data:
61/387,207 28.09.2010 US
Title (EN) FUSED TRICYCLIC INHIBITORS OF MAMMALIAN TARGET OF RAPAMYCIN
(FR) COMPOSÉS TRICYCLIQUES ACCOLÉS INHIBITEURS DE LA CIBLE MAMMIFÈRE DE LA RAPAMYCINE
Abstract: front page image
(EN)This invention relates to novel fused tricyclic compounds that are inhibitors of mammalian Target of Rapamycin (mTOR) kinase, which is also known as FRAP, RAFT, RAPT or SEP, and are useful in the treatment of cellular proliferative diseases, for example cancer and other proliferative disorders.
(FR)La présente invention concerne de nouveaux composés tricycliques accolés qui sont des inhibiteurs de la kinase de la cible mammifère de la rapamycine (mTOR), également connue sous le nom de FRAP, RAFT, RAPT ou SEP, et sont utiles pour le traitement de troubles de prolifération cellulaire, par exemple du cancer et d'autres troubles de prolifération.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)