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1. (WO2012047063) PHARMACEUTICAL COMPOSITION FOR AIDING DEMENTIA TREATMENT OR TREATING DEMENTIA, CONTAINING ANGELICA GIGAS NAKAI EXTRACT ONLY, GINKGO LEAF EXTRACT ONLY, OR MIXTURE OF ANGELICA GIGAS NAKAI EXTRACT AND GINKGO LEAF EXTRACT
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/047063    International Application No.:    PCT/KR2011/007451
Publication Date: 12.04.2012 International Filing Date: 07.10.2011
IPC:
A61K 36/232 (2006.01), A61K 36/16 (2006.01), A61P 25/28 (2006.01), A61P 25/00 (2006.01)
Applicants: JEIL PHARMACEUTICAL CO., LTD. [KR/KR]; 745-5 Banpo-dong Seocho-gu Seoul 137-040 (KR) (For All Designated States Except US).
KIM, Myung-Hwa [KR/KR]; (KR) (For US Only).
KU, Sae-Kwang [KR/KR]; (KR) (For US Only).
YE, In-Hae [KR/KR]; (KR) (For US Only).
LEE, Han-Chang [KR/KR]; (KR) (For US Only).
KIM, Kang-Jeon [KR/KR]; (KR) (For US Only)
Inventors: KIM, Myung-Hwa; (KR).
KU, Sae-Kwang; (KR).
YE, In-Hae; (KR).
LEE, Han-Chang; (KR).
KIM, Kang-Jeon; (KR)
Agent: LEE, Won Hee; 8th Fl. Sung-ji Heights II 642-16, Yoksam-dong, Kangnam-ku Seoul 135-080 (KR)
Priority Data:
10-2010-0098349 08.10.2010 KR
10-2011-0102105 06.10.2011 KR
Title (EN) PHARMACEUTICAL COMPOSITION FOR AIDING DEMENTIA TREATMENT OR TREATING DEMENTIA, CONTAINING ANGELICA GIGAS NAKAI EXTRACT ONLY, GINKGO LEAF EXTRACT ONLY, OR MIXTURE OF ANGELICA GIGAS NAKAI EXTRACT AND GINKGO LEAF EXTRACT
(FR) COMPOSITION PHARMACEUTIQUE POUR AIDER AU TRAITEMENT DE LA DÉMENCE OU POUR TRAITER LA DÉMENCE, CONTENANT SEULEMENT UN EXTRAIT D'ANGELICA GIGAS NAKAI, SEULEMENT UN EXTRAIT DE FEUILLE DE GINKGO, OU UN MÉLANGE D'EXTRAIT D'ANGELICA GIGAS NAKAI ET D'EXTRAIT DE FEUILLE DE GINKGO
(KO) 당귀 추출물, 은행엽 추출물 단독; 또는 당귀 추출물 및 은행엽 추출물의 혼합물을 포함하는 치매 치료보조용 또는 치매치료용 약학적 조성물
Abstract: front page image
(EN)The present invention relates to a pharmaceutical composition for aiding dementia treatment or treating dementia, containing an Angelica gigas Nakai extract only, a ginkgo leaf extract only, or a mixture of an Angelica gigas Nakai extract and ginkgo leaf extract. According to the present invention, the Angelica gigas Nakai extract only, the ginkgo leaf extract only, or the mixture of an Angelica gigas Nakai extract and a ginkgo leaf extract reduces toxicity and increases the median lethal dose (LD50) to reduce the toxicity of a dementia therapeutic agent, and increases pharmacodynamic values as an assistant of the dementia therapeutic agent, and thus can be useful in a pharmaceutical composition for aiding dementia treatment or treating dementia.
(FR)La présente invention porte sur une composition pharmaceutique pour aider au traitement de la démence ou pour traiter la démence, contenant seulement un extrait d'Angelica gigas Nakai, seulement un extrait de feuille de ginkgo, ou un mélange d'un extrait d'Angelica gigas Nakai et d'un extrait de feuille de ginkgo. Selon la présente invention, le seul extrait d'Angelica gigas Nakai, le seul extrait de feuille de ginkgo, ou le mélange d'un extrait d'Angelica gigas Nakai et d'un extrait de feuille de ginkgo réduit la toxicité et augmente la dose létale médiane (DL50) pour réduire la toxicité d'un agent thérapeutique de la démence, et augmente des valeurs pharmacodynamiques en tant qu'assistant de l'agent thérapeutique de la démence, et peut ainsi être utile dans une composition pharmaceutique pour aider au traitement de la démence ou pour traiter la démence.
(KO)본 발명은 당귀 추출물, 은행엽 추출물 단독; 또는 당귀 추출물 및 은행엽 추출물의 혼합물을 포함하는 치매 치료보조용 및 치매치료용 약학적 조성물에 관한 것으로, 본 발명에 따른 당귀 추출물, 은행엽 추출물 단독; 또는 당귀 추출물 및 은행엽 추출물의 혼합물은 독성을 감소시키고, 반수치사량(LD50)을 증가시켜 치매치 료제의 독성을 감소시키고, 치매치료제의 보조제로서 약물동력학적 수치들을 증가 시키므로 치매 치료보조용 또는 치매치료용 약학적 조성물로서 유용하게 사용될 수 있다.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Korean (KO)
Filing Language: Korean (KO)