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Pub. No.:    WO/2012/046882    International Application No.:    PCT/JP2011/073745
Publication Date: 12.04.2012 International Filing Date: 05.10.2011
C07D 267/10 (2006.01), C07D 413/04 (2006.01), C07D 413/06 (2006.01), C07D 413/10 (2006.01), C07D 413/12 (2006.01), C07D 413/14 (2006.01), C07D 417/06 (2006.01), C07D 417/14 (2006.01)
Applicants: TAKEDA PHARMACEUTICAL COMPANY LIMITED [JP/JP]; 1-1, Doshomachi 4-chome, Chuo-ku, Osaka-shi, Osaka 5410045 (JP) (For All Designated States Except US).
ISHICHI, Yuji [JP/JP]; (JP) (For US Only).
YAMADA, Masami [JP/US]; (US) (For US Only).
KAMEI, Taku [JP/JP]; (JP) (For US Only).
FUJIMORI, Ikuo [JP/US]; (US) (For US Only).
NAKADA, Yoshihisa [JP/JP]; (JP) (For US Only).
YUKAWA, Tomoya [JP/JP]; (JP) (For US Only).
SAKAUCHI, Nobuki [JP/JP]; (JP) (For US Only).
OHBA, Yusuke [JP/JP]; (JP) (For US Only).
TSUKAMOTO, Tetsuya [JP/JP]; (JP) (For US Only)
Inventors: ISHICHI, Yuji; (JP).
YAMADA, Masami; (US).
KAMEI, Taku; (JP).
NAKADA, Yoshihisa; (JP).
YUKAWA, Tomoya; (JP).
SAKAUCHI, Nobuki; (JP).
OHBA, Yusuke; (JP).
TSUKAMOTO, Tetsuya; (JP)
Agent: TAKASHIMA, Hajime; Meiji Yasuda Seimei Osaka Midosuji Bldg., 1-1, Fushimimachi 4-chome, Chuo-ku, Osaka-shi, Osaka 5410044 (JP)
Priority Data:
2010-227864 07.10.2010 JP
2011-175336 10.08.2011 JP
Abstract: front page image
(EN)Provided is a compound having a monoamine reuptake inhibitory activity, which is represented by the formula (I) wherein ring A is an optionally substituted 6-membered aromatic ring, ring B is the substituents on ring A are optionally bonded to form, together with ring A, an optionally substituted 9- or 10-membered aromatic fused ring, and other symbols are as defined in the specification, or a salt thereof.
(FR)L'invention concerne un composé ayant une activité inhibitrice de la réabsorption de la monoamine, représenté par la formule (I), le cycle A étant un cycle aromatique à 6 éléments, le cycle B étant les substituants sur le cycle A éventuellement liés pour former, conjointement avec le cycle A, un cycle aromatique fusionné à 9 ou 10 éléments éventuellement substitué, d'autres symboles étant définis dans la spécification; ou un sel dudit composé.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)