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1. (WO2012041124) AZABICYCLO OCTANE DERIVATIVES, PREPARATION PROCESS AND PHARMACEUTICAL USE THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/041124    International Application No.:    PCT/CN2011/078217
Publication Date: 05.04.2012 International Filing Date: 10.08.2011
IPC:
C07D 209/52 (2006.01), C07D 409/12 (2006.01), A61K 31/403 (2006.01), A61P 25/22 (2006.01), A61P 25/24 (2006.01)
Applicants: SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD. [CN/CN]; 279 Wenjing Road Minhang District Shanghai 200245 (CN) (For All Designated States Except US).
JIANGSU HENGRUI MEDICINE CO., LTD. [CN/CN]; No.7 Kunlunshan Road,Economic and Technological Development Zone Lianyungang, Jiangsu 222047 (CN) (For All Designated States Except US).
TU, Wangyang [CN/CN]; (CN) (For US Only).
YANG, Fanglong [CN/CN]; (CN) (For US Only).
GE, Jian [CN/CN]; (CN) (For US Only).
TANG, Peng Cho [CN/CN]; (CN) (For US Only).
XU, Guoji [CN/CN]; (CN) (For US Only)
Inventors: TU, Wangyang; (CN).
YANG, Fanglong; (CN).
GE, Jian; (CN).
TANG, Peng Cho; (CN).
XU, Guoji; (CN)
Agent: GE CHENG & CO. LTD.; Level 19, Tower E3, The Towers, Oriental Plaza No.1, East Chang An Avenue Dongcheng District, Beijing 100738 (CN)
Priority Data:
201010505288.X 28.09.2010 CN
Title (EN) AZABICYCLO OCTANE DERIVATIVES, PREPARATION PROCESS AND PHARMACEUTICAL USE THEREOF
(FR) DÉRIVÉS D'AZABICYCLO OCTANE, PROCÉDÉ DE PRÉPARATION ET LEUR UTILISATION PHARMACEUTIQUE
(ZH) 氮杂双环辛烷类衍生物、其制备方法及其在医药上的应用
Abstract: front page image
(EN)The present disclosure relates to azabicyclo octane derivatives,preparation processes and pharmaceutical compositions containing them. Specifically, the present disclosure relates to novel azabicyclo octane derivatives presented by formula (I), the uses for treatmente specially for dopamine, norepinephrine and serotonin reuptake inhibitors, in which each substitute group of general formula (I) is as defined in the specification.
(FR)La présente invention concerne des dérivés d'azabicyclo octane, des procédés de préparation et des compositions pharmaceutiques les contenant. De façon spécifique, la présente invention concerne de nouveaux dérivés d'azabicyclo octane représentés par la formule (I), les utilisations pour le traitement notamment d'inhibiteurs de recapture de la dopamine, de la norépinéphrine et de la sérotonine, chaque groupe de substitution de la formule générale (I) étant tel que défini dans la description.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)