WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2012041014) TETRACYCLIC INDOLE DERIVATIVES FOR TREATING HEPATITIS C VIRUS INFECTION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/041014    International Application No.:    PCT/CN2011/001638
Publication Date: 05.04.2012 International Filing Date: 28.09.2011
IPC:
C07D 498/04 (2006.01), C07D 487/04 (2006.01), C07D 471/04 (2006.01), A61K 31/5365 (2006.01), A61K 31/4985 (2006.01), A61K 31/437 (2006.01), A61P 31/14 (2006.01)
Applicants: MERCK SHARP & DOHME CORP. [US/US]; 126 East Lincoln Avenue Rahway, New Jersey 07065-0907 (US) (For All Designated States Except US).
KOZLOWSKI, Joseph A. [US/US]; (US) (For US Only).
ROSENBLUM, Stuart B. [US/US]; (US) (For US Only).
COBURN, Craig A. [US/US]; (US) (For US Only).
SHANKAR, Bandarpalle, B. [US/US]; (US) (For US Only).
ANILKUMAR, G., Nair [US/US]; (US) (For US Only).
CHEN, Lei [CN/US]; (US) (For US Only).
DWYER, Michael, P. [US/US]; (US) (For US Only).
JIANG, Yueheng [US/US]; (US) (For US Only).
KEERTIKAR, Kartik, M. [US/US]; (US) (For US Only).
LAVEY, Brian, J. [US/US]; (US) (For US Only).
SELYUTIN, Oleg, B. [US/US]; (US) (For US Only).
TONG, Ling [CN/US]; (US) (For US Only).
WONG, Michael [CA/US]; (US) (For US Only).
YANG, De-Yi [US/US]; (US) (For US Only).
YU, Wensheng [CN/US]; (US) (For US Only).
ZHOU, Guowei [US/US]; (US) (For US Only).
WU, Hao [CN/CN]; (CN) (For US Only).
HU, Bin [CN/CN]; (CN) (For US Only).
ZHONG, Bin [CN/CN]; (CN) (For US Only).
SUN, Fei [CN/CN]; (CN) (For US Only).
JI, Tao [CN/CN]; (CN) (For US Only).
SHEN, Changmao [CN/CN]; (CN) (For US Only).
RIZVI, Razia [US/US]; (US) (For US Only).
ZENG, Qingbei [CN/US]; (US) (For US Only)
Inventors: KOZLOWSKI, Joseph A.; (US).
ROSENBLUM, Stuart B.; (US).
COBURN, Craig A.; (US).
SHANKAR, Bandarpalle, B.; (US).
ANILKUMAR, G., Nair; (US).
CHEN, Lei; (US).
DWYER, Michael, P.; (US).
JIANG, Yueheng; (US).
KEERTIKAR, Kartik, M.; (US).
LAVEY, Brian, J.; (US).
SELYUTIN, Oleg, B.; (US).
TONG, Ling; (US).
WONG, Michael; (US).
YANG, De-Yi; (US).
YU, Wensheng; (US).
ZHOU, Guowei; (US).
WU, Hao; (CN).
HU, Bin; (CN).
ZHONG, Bin; (CN).
SUN, Fei; (CN).
JI, Tao; (CN).
SHEN, Changmao; (CN).
RIZVI, Razia; (US).
ZENG, Qingbei; (US)
Agent: LIU, SHEN & ASSOCIATES; A0601, Huibin Building No.8 Beichen Dong Street, Chaoyang District Beijing 100101 (CN)
Priority Data:
PCT/CN2010/077493 29.09.2010 CN
61/426,724 23.12.2010 US
Title (EN) TETRACYCLIC INDOLE DERIVATIVES FOR TREATING HEPATITIS C VIRUS INFECTION
(FR) DÉRIVÉS D'INDOLES TÉTRACYCLIQUES POUR LE TRAITEMENT D'UNE INFECTION PAR LE VIRUS DE L'HÉPATITE C
Abstract: front page image
(EN)Tetracyclic indole derivatives of formula (I), pharmaceutically acceptable salts and the pharmaceutical compositions thereof are provided, wherein A, A', G, R1, R15, U, V, V, W, W, X, X', Y, Y' are as defined in the invention. Use of these derivatives for treating hepatitis C virus (HCV) infection is also provided.
(FR)La présente invention concerne des dérivés d'indoles tétracycliques de formule (I), leurs sels pharmaceutiquement acceptables et leurs compositions pharmaceutiques, dans laquelle A, A', G, R1, R15, U, V, V, W, W, X, X', Y, Y' sont tels que définis dans l'invention. L'invention concerne également l'utilisation desdits dérivés pour le traitement d'une infection par le virus de l'hépatite C (VHC).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)