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1. WO2012032534 - FURANOSE DERIVATIVES AND THEIR APPLICATIONS IN SYNTHESIS OF STATINS

Publication Number WO/2012/032534
Publication Date 15.03.2012
International Application No. PCT/IN2011/000523
International Filing Date 08.08.2011
IPC
C07D 303/26 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
303Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
02Compounds containing oxirane rings
12with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
18by etherified hydroxyl radicals
20Ethers with hydroxy compounds containing no oxirane rings
24with polyhydroxy compounds
26having one or more free hydroxyl radicals
C07D 307/32 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
307Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
02not condensed with other rings
26having one double bond between ring members or between a ring member and a non-ring member
30with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
32Oxygen atoms
C07D 307/60 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
307Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
02not condensed with other rings
34having two or three double bonds between ring members or between ring members and non-ring members
56with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
60Two oxygen atoms, e.g. succinic anhydride
C07D 407/12 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
407Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/183
02containing two hetero rings
12linked by a chain containing hetero atoms as chain links
C07C 255/07 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
255Carboxylic acid nitriles
01having cyano groups bound to acyclic carbon atoms
06of an acyclic and unsaturated carbon skeleton
07Mononitriles
C07C 317/04 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
317Sulfones; Sulfoxides
02having sulfone or sulfoxide groups bound to acyclic carbon atoms
04of an acyclic saturated carbon skeleton
CPC
C07C 255/14
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
255Carboxylic acid nitriles
01having cyano groups bound to acyclic carbon atoms
11containing cyano groups and singly-bound oxygen atoms bound to the same saturated acyclic carbon skeleton
14containing cyano groups and esterified hydroxy groups bound to the carbon skeleton
C07C 309/66
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
309Sulfonic acids; Halides, esters, or anhydrides thereof
63Esters of sulfonic acids
64having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
65of a saturated carbon skeleton
66Methanesulfonates
C07D 303/26
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
303Compounds containing three-membered rings having one oxygen atom as the only ring heteroatom
02Compounds containing oxirane rings
12with hydrocarbon radicals substituted by singly or doubly bound oxygen atoms
18by etherified hydroxyl radicals
20Ethers with hydroxy compounds containing no oxirane rings
24with polyhydroxy compounds
26having one or more free hydroxyl radicals
C07D 307/32
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
307Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
02not condensed with other rings
26having one double bond between ring members or between a ring member and a non-ring member
30with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
32Oxygen atoms
C07D 307/60
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
307Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
02not condensed with other rings
34having two or three double bonds between ring members or between ring members and non-ring members
56with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
60Two oxygen atoms, e.g. succinic anhydride
C07D 407/12
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
407Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
02containing two hetero rings
12linked by a chain containing hetero atoms as chain links
Applicants
  • HELVETICA INDUSTRIES (P) LIMITED [IN]/[IN] (AllExceptUS)
  • PRADHAN, Braja, Sunder [IN]/[IN] (UsOnly)
  • GHOSH, Prasanta, K [IN]/[IN] (UsOnly)
  • RANGARAO, Ch [IN]/[IN] (UsOnly)
  • VEMPALA, Naresh [IN]/[IN] (UsOnly)
  • APPARAO, Thoomu [IN]/[IN] (UsOnly)
Inventors
  • PRADHAN, Braja, Sunder
  • GHOSH, Prasanta, K
  • RANGARAO, Ch
  • VEMPALA, Naresh
  • APPARAO, Thoomu
Agents
  • TRIPATHI, Vishal
Priority Data
1583/DEL/201006.09.2010IN
2641/DEL/201003.11.2010IN
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) FURANOSE DERIVATIVES AND THEIR APPLICATIONS IN SYNTHESIS OF STATINS
(FR) DÉRIVÉS DE FURANOSE ET LEURS APPLICATIONS DANS LA SYNTHÈSE DE STATINES
Abstract
(EN)
The present invention relates to compounds of formula XXII and their synthesis from furanose derivatives as shown hereunder. Compounds of formula XXII are of use in the synthesis of statins.
(FR)
L'invention concerne des dérivés de furanose et leurs applications dans la synthèse de statines.
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