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1. WO2012032534 - FURANOSE DERIVATIVES AND THEIR APPLICATIONS IN SYNTHESIS OF STATINS

Publication Number WO/2012/032534
Publication Date 15.03.2012
International Application No. PCT/IN2011/000523
International Filing Date 08.08.2011
IPC
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
303
Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
02
Compounds containing oxirane rings
12
with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
18
by etherified hydroxyl radicals
20
Ethers with hydroxy compounds containing no oxirane rings
24
with polyhydroxy compounds
26
having one or more free hydroxyl radicals
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
307
Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
02
not condensed with other rings
26
having one double bond between ring members or between a ring member and a non-ring member
30
with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
32
Oxygen atoms
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
307
Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
02
not condensed with other rings
34
having two or three double bonds between ring members or between ring members and non-ring members
56
with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
60
Two oxygen atoms, e.g. succinic anhydride
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
407
Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/183
02
containing two hetero rings
12
linked by a chain containing hetero atoms as chain links
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
255
Carboxylic acid nitriles
01
having cyano groups bound to acyclic carbon atoms
06
of an acyclic and unsaturated carbon skeleton
07
Mononitriles
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
317
Sulfones; Sulfoxides
02
having sulfone or sulfoxide groups bound to acyclic carbon atoms
04
of an acyclic saturated carbon skeleton
C07D 303/26 (2006.01)
C07D 307/32 (2006.01)
C07D 307/60 (2006.01)
C07D 407/12 (2006.01)
C07C 255/07 (2006.01)
C07C 317/04 (2006.01)
CPC
C07C 255/14
C07C 309/66
C07D 303/26
C07D 307/32
C07D 307/60
C07D 407/12
Applicants
  • HELVETICA INDUSTRIES (P) LIMITED [IN/IN]; A-1, Community Center Naraina Industrial Area, Phase II New Delhi 110 028, IN (AllExceptUS)
  • PRADHAN, Braja, Sunder [IN/IN]; IN (UsOnly)
  • GHOSH, Prasanta, K [IN/IN]; IN (UsOnly)
  • RANGARAO, Ch [IN/IN]; IN (UsOnly)
  • VEMPALA, Naresh [IN/IN]; IN (UsOnly)
  • APPARAO, Thoomu [IN/IN]; IN (UsOnly)
Inventors
  • PRADHAN, Braja, Sunder; IN
  • GHOSH, Prasanta, K; IN
  • RANGARAO, Ch; IN
  • VEMPALA, Naresh; IN
  • APPARAO, Thoomu; IN
Agents
  • TRIPATHI, Vishal; Inttl Advocare D-22, 2nd Floor Panchsheel Enclave New Delhi 110 017, IN
Priority Data
1583/DEL/201006.09.2010IN
2641/DEL/201003.11.2010IN
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) FURANOSE DERIVATIVES AND THEIR APPLICATIONS IN SYNTHESIS OF STATINS
(FR) DÉRIVÉS DE FURANOSE ET LEURS APPLICATIONS DANS LA SYNTHÈSE DE STATINES
Abstract
(EN)
The present invention relates to compounds of formula XXII and their synthesis from furanose derivatives as shown hereunder. Compounds of formula XXII are of use in the synthesis of statins.
(FR)
L'invention concerne des dérivés de furanose et leurs applications dans la synthèse de statines.
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