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1. (WO2012021247) INNOVATIVE DISCOVERY OF THERAPEUTIC, DIAGNOSTIC, AND ANTIBODY COMPOSITIONS RELATED TO PROTEIN FRAGMENTS OF GLYCYL-TRNA SYNTHETASES
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2012/021247 International Application No.: PCT/US2011/043756
Publication Date: 16.02.2012 International Filing Date: 12.07.2011
IPC:
A61K 38/16 (2006.01) ,A61K 38/10 (2006.01) ,A61K 38/08 (2006.01) ,A61K 39/395 (2006.01) ,A61P 35/00 (2006.01) ,A61P 3/10 (2006.01) ,A61P 3/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
04
Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
10
Peptides having 12 to 20 amino acids
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
04
Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
08
Peptides having 5 to 11 amino acids
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3
Drugs for disorders of the metabolism
08
for glucose homeostasis
10
for hyperglycaemia, e.g. antidiabetics
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3
Drugs for disorders of the metabolism
Applicants:
GREENE, Leslie, Ann [US/US]; US (UsOnly)
CHIANG, Kyle, P. [US/US]; US (UsOnly)
HONG, Fei [CN/US]; US (UsOnly)
VASSEROT, Alain, P. [CH/US]; US (UsOnly)
LO, Wing-Sze [CN/CN]; HK (UsOnly)
WATKINS, Jeffry, D. [US/US]; US (UsOnly)
QUINN, Cheryl, L. [US/US]; US (UsOnly)
MENDLEIN, John, D. [US/US]; US (UsOnly)
ATYR PHARMA, INC. [US/US]; 3545 John Hopkins Court, Suite #250 San Diego, CA 92121, US (AllExceptUS)
PANGU BIOPHARMA LIMITED [CN/CN]; 18/F Edinburgh Tower, The Landmark, 15 Queen's Road Central Hong Kong, HK (AllExceptUS)
Inventors:
GREENE, Leslie, Ann; US
CHIANG, Kyle, P.; US
HONG, Fei; US
VASSEROT, Alain, P.; US
LO, Wing-Sze; HK
WATKINS, Jeffry, D.; US
QUINN, Cheryl, L.; US
MENDLEIN, John, D.; US
Agent:
ROGEL, Mark, E.; Cooley LLP 777 6th Street, NW Suite 1100 Washington, District of Columbia 20001, US
Priority Data:
61/363,44912.07.2010US
61/363,45612.07.2010US
61/363,46112.07.2010US
61/488,34920.05.2011US
61/488,35120.05.2011US
61/488,35720.05.2011US
Title (EN) INNOVATIVE DISCOVERY OF THERAPEUTIC, DIAGNOSTIC, AND ANTIBODY COMPOSITIONS RELATED TO PROTEIN FRAGMENTS OF GLYCYL-TRNA SYNTHETASES
(FR) DÉCOUVERTE INNOVANTE DE COMPOSITIONS THÉRAPEUTIQUES, DE DIAGNOSTIC ET D'ANTICORPS SE RAPPORTANT À DES FRAGMENTS PROTÉIQUES DE GLYCYL-ARNt SYNTHÉTASES
Abstract:
(EN) Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.
(FR) L'invention concerne des compositions qui renferment des fragments protéiques nouvellement identifiés d'aminoacyl-ARNt synthétases, des polynucléotides codant ces fragments et des compléments de ceux-ci, des agents associés et des méthodes d'utilisation de ces fragments dans des applications diagnostiques et thérapeutiques, ainsi que dans des applications de recherche et de découverte de médicaments.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)