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1. (WO2011163661) IMPLANTABLE MAGNETIC RELAXATION SENSORS AND METHODS OF MEASURING A SENSOR'S CUMULATIVE EXPOSURE TO A BIOMARKER
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/163661    International Application No.:    PCT/US2011/042022
Publication Date: 29.12.2011 International Filing Date: 27.06.2011
Chapter 2 Demand Filed:    25.04.2012    
IPC:
A61M 37/00 (2006.01), A61N 2/00 (2006.01)
Applicants: MASSACHUSETTS INSTITUTE OF TECHNOLOGY [US/US]; 77 Massachusetts Avenue Cambridge, MA 02139 (US) (For All Designated States Except US).
THE GENERAL HOSPITAL COPRORATION [US/US]; 55 Fruit Street Boston, Massachusetts 02114 (US) (For All Designated States Except US).
CIMA, Michael, J. [US/US]; (US) (For US Only).
HUANG, Paul [US/US]; (US) (For US Only).
LING, Yibo [US/US]; (US) (For US Only).
PONG, Terrence [US/US]; (US) (For US Only).
VASSILIOU, Christophoros, C. [US/US]; (US) (For US Only)
Inventors: CIMA, Michael, J.; (US).
HUANG, Paul; (US).
LING, Yibo; (US).
PONG, Terrence; (US).
VASSILIOU, Christophoros, C.; (US)
Agent: KING, Kevin, W.; Sutherland Asbill & Brennan LLP 999 Peachtree Street, NE Atlanta, GA 30309-3996 (US)
Priority Data:
61/358,449 25.06.2010 US
Title (EN) IMPLANTABLE MAGNETIC RELAXATION SENSORS AND METHODS OF MEASURING A SENSOR'S CUMULATIVE EXPOSURE TO A BIOMARKER
(FR) CAPTEURS DE RELAXATION MAGNÉTIQUE IMPLANTABLES ET PROCÉDÉS DE MESURE D'EXPOSITION CUMULATIVE DE CAPTEUR À UN MARQUEUR BIOLOGIQUE
Abstract: front page image
(EN)An implantable magnetic relaxation sensor is provided that comprises superparamagnetic nanoparticies functionalized with one or more agents that bond with a biomarker of interest. The sensor is configured for minimally-invasive implantation into a human or animal, and is configured to indicate the implanted sensor's cumulative exposure to the biomarker of interest by analysis using magnetic resonance relaxometry.
(FR)L'invention porte sur un capteur de relaxation magnétique implantable qui comprend des nanoparticules super paramagnétiques, fonctionnalisées avec un ou plusieurs agents qui sont liés à un marqueur biologique d'intérêt. Le capteur, qui est configuré pour une implantation minimalement invasive dans le corps d'un être humain ou d'un animal, est configuré pour indiquer l'exposition cumulative du capteur implanté au marqueur biologique d'intérêt par analyse à l'aide d'une relaxométrie par résonance magnétique.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)