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Machine translation
1. (WO2011162627) A METHOD OF PRODUCING BACTERIOPHAGES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/162627    International Application No.:    PCT/PL2011/050026
Publication Date: 29.12.2011 International Filing Date: 20.06.2011
IPC:
C12N 7/02 (2006.01), C07K 14/01 (2006.01)
Applicants: INSTYTUT IMMUNOLOGII I TERAPII DOŚWIADCZALNEJ PAN [PL/PL]; Weigla 12 PL-53-114 Wrocław (PL) (For All Designated States Except US).
DąBROWSKA, Krystyna [PL/PL]; (PL) (For US Only).
OśLIZŁO, Anna [PL/PL]; (PL) (For US Only).
BUDYNEK, Paulina [PL/PL]; (PL) (For US Only).
PIOTROWICZ, Agnieszka [PL/PL]; (PL) (For US Only).
GÓRSKI, Andrzej [PL/PL]; (PL) (For US Only)
Inventors: DąBROWSKA, Krystyna; (PL).
OśLIZŁO, Anna; (PL).
BUDYNEK, Paulina; (PL).
PIOTROWICZ, Agnieszka; (PL).
GÓRSKI, Andrzej; (PL)
Agent: WITEK, Rafał; WTS Patent Attorneys Witek, Śnieżko & Partners Weigla 12 PL-53-114 Wrocław (PL)
Priority Data:
PL391551 20.06.2010 PL
Title (EN) A METHOD OF PRODUCING BACTERIOPHAGES
(FR) PROCÉDÉ DE PRODUCTION DE BACTÉRIOPHAGES
Abstract: front page image
(EN)The proposed method permits the single-stage and effective purification of phage preparations of therapeutic significance, makes it possible to retain the antibacterial activities of bacteriophages, both in the case of a strategy based on the displacement of bound bacteriophages from the gel as well as on proteolytic release. Modification of phage capsid proteins with appropriate binding motifs makes it possible to purify therapeutic strains of bacteriophages using affinity chromatography.
(FR)L'invention concerne un procédé permettant la purification efficace et en une seule étape de préparations de phages de portée thérapeutique, rendant possible la conservation des activités antibactériennes des bactériophages, à la fois dans le cas d'une stratégie basée sur le déplacement de bactériophages liés à partir du gel ainsi qu'une libération protéolytique. Une modification de protéines de capside de phage par des motifs de liaison appropriés rend possible la purification de souches thérapeutiques de bactériophages par chromatographie d'affinité.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)