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1. (WO2011161545) NON-HYDROLYZABLE PROTEIN CONJUGATES, METHODS AND COMPOSITIONS RELATED THERETO
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/161545    International Application No.:    PCT/IB2011/002024
Publication Date: 29.12.2011 International Filing Date: 06.06.2011
IPC:
C07K 19/00 (2006.01), C07K 1/107 (2006.01)
Applicants: THE NETHERLANDS CANCER INSTITUTE [NL/NL]; Plesmanlaan 121 NL-1066 CX Amsterdam (NL) (For All Designated States Except US).
OVAA, Huib [NL/NL]; (NL) (For US Only).
SHANMUGHAM, Anitha [NL/NL]; (NL) (For US Only).
EKKEBUS, Reggy [NL/NL]; (NL) (For US Only).
EL OUALID, Farid [NL/NL]; (NL) (For US Only).
MERKX, Remco [NL/NL]; (NL) (For US Only)
Inventors: OVAA, Huib; (NL).
SHANMUGHAM, Anitha; (NL).
EKKEBUS, Reggy; (NL).
EL OUALID, Farid; (NL).
MERKX, Remco; (NL)
Priority Data:
61/351,659 04.06.2010 US
61/353,780 11.06.2010 US
Title (EN) NON-HYDROLYZABLE PROTEIN CONJUGATES, METHODS AND COMPOSITIONS RELATED THERETO
(FR) CONJUGUÉS PROTÉIQUES NON HYDROLYSABLES, PROCÉDÉS ET COMPOSITIONS AFFÉRENTS
Abstract: front page image
(EN)The invention provides compositions and methods relating to non-hydrolyzable post- translational protein modifications, such as, for example, non-hydrolyzable ubiquitin and ubiquitin-like protein conjugates. In some embodiments, the invention relates to antibodies, such as linkage-specific antibodies, directed against a protein conjugate of the invention.
(FR)Les compositions et les procédés ci-décrits concernent des modifications post-traductionnelles non hydrolysables de protéines, telles que, par exemple, des conjugués protéiques d'ubiquitine et d'ubiquitine-like non hydrolysables. Dans certains modes de réalisation, l'invention concerne des anticorps, tels que des anticorps spécifiques de liaisons, dirigés contre un conjugué protéique selon l'invention.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)