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1. (WO2011160149) NOVEL SORBENT FOR ENDOTOXINS

Pub. No.:    WO/2011/160149    International Application No.:    PCT/AT2011/000273
Publication Date: Dec 29, 2011 International Filing Date: Jun 22, 2011
IPC: A61M 1/36
B01D 15/00
B01J 20/26
B01J 20/32
Applicants: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
FALKENHAGEN, Dieter
HARM, Stephan
HARTMANN, Jens
WEBER, Viktoria
Inventors: FALKENHAGEN, Dieter
HARM, Stephan
HARTMANN, Jens
WEBER, Viktoria
Title: NOVEL SORBENT FOR ENDOTOXINS
Abstract:
The invention relates to a sorbent for removing endotoxins from a biological liquid, comprising a water-insoluble, porous substrate having a neutral, hydrophobic surface, wherein the surface of the substrate has an adsorbent coating made of polymyxin and albumin, wherein polymyxin and albumin are bonded to the surface of the substrate in a noncovalent manner. The invention further relates to a method for producing such a sorbent. The sorbent is used in extracorporeal blood purification, in particular in order to treat individuals who have sepsis.