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1. (WO2011159864) JTE013 ANALOGS AND METHODS OF MAKING AND USING SAME

Pub. No.:    WO/2011/159864    International Application No.:    PCT/US2011/040637
Publication Date: Dec 22, 2011 International Filing Date: Jun 16, 2011
IPC: A01N 47/34
A61K 31/17
A61K 31/175
Applicants: BRACCO IMAGING S.P.A.
SWENSON, Rolf, E.
RAJU, Natarajan
ESTRELLA-JIMENEZ, Maria, E.
RAMALINGAM, Kondareddiar
Inventors: SWENSON, Rolf, E.
RAJU, Natarajan
ESTRELLA-JIMENEZ, Maria, E.
RAMALINGAM, Kondareddiar
Title: JTE013 ANALOGS AND METHODS OF MAKING AND USING SAME
Abstract:
JTE013 analogs having similar or greater stability relative to JTE013 are provided. Also provided are JTE013 analogs which can bind to both S1P2 and S IP5, some of which also have similar or greater stability relative to JTE013. In addition, methods for the treatment and prevention of diseases and conditions associated with S1P2 and S IP5 receptors are provided.