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1. (WO2011158931) USEFUL SALTS OF INDAZOLE DERIVATIVE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/158931    International Application No.:    PCT/JP2011/063901
Publication Date: 22.12.2011 International Filing Date: 17.06.2011
IPC:
C07D 409/12 (2006.01), A61K 31/496 (2006.01), A61P 1/04 (2006.01), A61P 1/16 (2006.01), A61P 1/18 (2006.01), A61P 11/00 (2006.01), A61P 13/08 (2006.01), A61P 13/10 (2006.01), A61P 13/12 (2006.01), A61P 15/00 (2006.01), A61P 17/00 (2006.01), A61P 19/00 (2006.01), A61P 25/00 (2006.01), A61P 35/00 (2006.01), A61P 35/02 (2006.01)
Applicants: Kyowa Hakko Kirin Co., Ltd. [JP/JP]; 1-6-1, Ohtemachi, Chiyoda-ku, Tokyo 1008185 (JP) (For All Designated States Except US).
ISAMI, Syoichi; (For US Only).
MURAMATSU, Norikazu; (For US Only).
TANIMURA, Shinji; (For US Only)
Inventors: ISAMI, Syoichi; .
MURAMATSU, Norikazu; .
TANIMURA, Shinji;
Priority Data:
2010-138013 17.06.2010 JP
Title (EN) USEFUL SALTS OF INDAZOLE DERIVATIVE
(FR) SELS UTILES D'UN DÉRIVÉ D'INDAZOLE
(JA) インダゾール誘導体の有用な塩
Abstract: front page image
(EN)Provided are a p-toluenesulfonate of compound (I), a hydrochloride and other salts of said compound (I), and a pharmaceutical composition containing the p-toluenesulfonate, the hydrochloride, or the like of said compound (I) that have excellent physical properties and quality and that are useful in treating abnormal cell growth, such as cancer, by the action of inhibiting the type I insulin-like growth factor receptor (IGF-1R).
(FR)Cette invention concerne un p-toluènesulfonate du composé (I), un hydrochlorure et autres sels du composé (I) et une composition pharmaceutique contenant le p-toluènesulfonate, l'hydrochlorure ou analogue dudit composé (I) qui possèdent des caractéristiques et une qualité remarquables et qui conviennent pour le traitement d'un développement cellulaire anormal comme dans le cancer, en inhibant le récepteur du facteur de croissance analogue à l'insuline de type I.
(JA) I型インスリン様増殖因子受容体(IGF-1R)阻害作用を介して、癌等の異常な細胞増殖の治療に有用で、物性、品質等の優れた、下記の化合物(I)のp-トルエンスルホン酸塩、化合物(I)の塩酸塩等、及び化合物(I)のp-トルエンスルホン酸塩または塩酸塩等を含有する医薬組成物を提供する。 
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)