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1. (WO2011156202) SUBSTITUTED 2 '-AMINO AND 2 '-THIO-BICYCLIC NUCLEOSIDES AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/156202    International Application No.:    PCT/US2011/038931
Publication Date: 15.12.2011 International Filing Date: 02.06.2011
IPC:
C07H 19/073 (2006.01), C07H 21/04 (2006.01), C07H 19/173 (2006.01), C12N 15/113 (2010.01)
Applicants: ISIS PHARMACEUTICALS, INC. [US/US]; 2855 Gazelle Court Carlsbad, CA 92010 (US) (For All Designated States Except US).
SETH, Punit, P. [US/US]; (US) (For US Only).
PRAKASH, Thazha, P. [IN/US]; (US) (For US Only).
SWAYZE, Eric, E. [US/US]; (US) (For US Only)
Inventors: SETH, Punit, P.; (US).
PRAKASH, Thazha, P.; (US).
SWAYZE, Eric, E.; (US)
Agent: RIEGER, Dale, L.; Jones Day 222 East 41st St. New York, NY 10017-6702 (US)
Priority Data:
61/352,516 08.06.2010 US
Title (EN) SUBSTITUTED 2 '-AMINO AND 2 '-THIO-BICYCLIC NUCLEOSIDES AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM
(FR) 2'‑AMINO- ET 2'‑THIO-NUCLÉOSIDES BICYCLIQUES SUBSTITUÉS ET COMPOSÉS OLIGOMÈRES PRÉPARÉS À PARTIR DE CES DERNIERS
Abstract: front page image
(EN)Provided herein are 2'-amino and 2'-thio bicyclic nucleosides and oligomenc compounds prepared therefrom. The novel bicyclic nucleosides provided herein are expected to be useful for enhancing one or more properties of the oligomeric compounds they are incorporated into such as nuclease resistance.
(FR)La présente invention concerne des 2'-amino- et 2'-thio-nucléosides bicycliques et des composés oligomères préparés à partir de ces derniers. On s'attend à ce que lesdits nouveaux nucléosides bicycliques soient utiles pour amplifier une ou plusieurs propriétés des composés oligomères dans lesquels ils sont incorporés, telles que la résistance aux nucléases.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)