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1. (WO2011155822) TRISACCHARIDE DERIVATES, AND THEIR USE AS ADJUVANTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/155822    International Application No.:    PCT/NL2011/050393
Publication Date: 15.12.2011 International Filing Date: 03.06.2011
IPC:
C07H 13/06 (2006.01), A61K 39/39 (2006.01)
Applicants: IMMUNOVO B.V. [NL/NL]; Onderwijsboulevard 219 NL-5223 DE 's-Hertogenbosch (NL) (For All Designated States Except US).
VAN BREE, Johannes, Gernardus, Mathias, Marie [NL/NL]; (NL) (For US Only).
SCHENKELAARS, Everardus, Joannes, Peter, Maria [NL/NL]; (NL) (For US Only).
TURKSTRA, Jouwert, Anne [NL/NL]; (NL) (For US Only).
KRIEK, Maria, Aldegonda, Jacoba [NL/NL]; (NL) (For US Only).
HOF, Robert, Patrick [NL/NL]; (NL) (For US Only).
SCHAAPER, Wilhelmus, Martinus, Maria [NL/NL]; (NL) (For US Only)
Inventors: VAN BREE, Johannes, Gernardus, Mathias, Marie; (NL).
SCHENKELAARS, Everardus, Joannes, Peter, Maria; (NL).
TURKSTRA, Jouwert, Anne; (NL).
KRIEK, Maria, Aldegonda, Jacoba; (NL).
HOF, Robert, Patrick; (NL).
SCHAAPER, Wilhelmus, Martinus, Maria; (NL)
Agent: NEDERLANDSCH OCTROOIBUREAU; J.W. Frisolaan 13 NL-2517 The Hague (NL)
Priority Data:
10165707.0 11.06.2010 EP
Title (EN) TRISACCHARIDE DERIVATES, AND THEIR USE AS ADJUVANTS
(FR) DÉRIVÉS DE TRISACCHARIDE ET LEUR UTILISATION COMME ADJUVANTS
Abstract: front page image
(EN)The present invention relates to the use of trisaccharide derivates comprising a substituted trisaccharide core, which trisaccharide core is fully substituted with fatty acid ester groups, and optionally one or more anionic groups as adjuvants, to the trisaccharide derivates as such, to a method for preparing such trisaccharides, to trisaccharides obtained with such method, to adjuvant compositions comprising such trisaccharide derivates and to a vaccine or kit comprising such adjuvant compositions.
(FR)La présente invention concerne l'utilisation comme adjuvants de dérivés de trisaccharide comprenant un cœur trisaccharidique substitué, le cœur trisaccharidique étant totalement substitué avec des groupes esters d'acide gras, et éventuellement un ou plusieurs groupes anioniques, les dérivés de trisaccharide eux-mêmes, un procédé de préparation de ces trisaccharides, les trisaccharides obtenus par ce procédé, des compositions d'adjuvants comprenant ces dérivés de trisaccharide et un vaccin ou un kit comprenant ces compositions d'adjuvants.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)