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1. (WO2011155579) ANTI-Trop-2 ANTIBODY

Pub. No.:    WO/2011/155579    International Application No.:    PCT/JP2011/063294
Publication Date: Dec 15, 2011 International Filing Date: Jun 9, 2011
IPC: C07K 16/28
A61K 39/395
A61K 45/00
C12N 5/10
C12N 15/09
C12P 21/08
Applicants: SAPPORO MEDICAL UNIVERSITY
北海道公立大学法人札幌医科大学
Kyowa Hakko Kirin Co., Ltd.
協和発酵キリン株式会社
YAMAGUCHI Miki
山口 美樹
KATO Kazunori
加藤 和則
HAMADA Hirofumi
濱田 洋文
NAKAMURA Kazuyasu
中村 和靖
SUGIMOTO Yoshiyuki
杉本 義幸
KUBOTA Tsuguo
久保田 麗夫
IKEDA Masahiro
池田 昌弘
Inventors: YAMAGUCHI Miki
山口 美樹
KATO Kazunori
加藤 和則
HAMADA Hirofumi
濱田 洋文
NAKAMURA Kazuyasu
中村 和靖
SUGIMOTO Yoshiyuki
杉本 義幸
KUBOTA Tsuguo
久保田 麗夫
IKEDA Masahiro
池田 昌弘
Title: ANTI-Trop-2 ANTIBODY
Abstract:
Disclosed is an anti-Trop-2 antibody related to: a monoclonal antibody or antibody fragment against human Trop-2 that specifically binds to the human Trop-2 extracellular domain, a hybridoma that produces said antibody, DNA that codes said antibody, a vector that contains said DNA, a transformant obtained by introducing said vector; and a method for producing an antibody or antibody fragment that uses said hybridoma or said transformant, or a therapeutic drug or diagnostic agent that uses said antibody fragment.