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1. (WO2011154895) POLYNUCLEOTIDE SEQUENCE, PROCESSES, COMPOSITION AND METHODS THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/154895    International Application No.:    PCT/IB2011/052475
Publication Date: 15.12.2011 International Filing Date: 07.06.2011
Chapter 2 Demand Filed:    02.04.2012    
IPC:
C12N 15/30 (2006.01), C07K 14/44 (2006.01), A61K 31/395 (2006.01), G01N 31/00 (2006.01)
Applicants: INDIAN INSTITUTE OF SCIENCE [IN/IN]; Bangalore, Karnataka 560 012 (IN) (For All Designated States Except US).
TATU, Utpal [IN/IN]; (IN) (For US Only).
PALLAVI, Rani [IN/IN]; (IN) (For US Only).
YADAV, Suresh, Chander [IN/IN]; (IN) (For US Only).
SINGH, Raj, Kumar [IN/IN]; (IN) (For US Only)
Inventors: TATU, Utpal; (IN).
PALLAVI, Rani; (IN).
YADAV, Suresh, Chander; (IN).
SINGH, Raj, Kumar; (IN)
Agent: VIJAYAKRISHNAN, Sindhu; K & S Partners # 4121/B, 6th Cross, 19A Main HAL II Stage (Extension) Bangalore 560 038 (IN)
Priority Data:
1575/CHE/2010 08.06.2010 IN
Title (EN) POLYNUCLEOTIDE SEQUENCE, PROCESSES, COMPOSITION AND METHODS THEREOF
(FR) SÉQUENCE POLYNUCLÉOTIDIQUE, PROCÉDÉS, COMPOSITION ET MÉTHODES ASSOCIÉS
Abstract: front page image
(EN)The present disclosure relates to a polynucleotide sequence coding for a protein of Trypanosoma species. The disclosure further provides processes for inhibiting said protein for treatment of protozoan infections, Malaria and Surra, by Geldanamycin and 17-AAG. The disclosure also relates to processes for identification of these inhibitions, compositions and method of treatments of said infections. Lastly, the present disclosure also relates to examining the efficacy of Hsp90 inhibitor as an anti-malarial and anti-surra agents.
(FR)La présente invention concerne une séquence polynucléotidique codant pour une protéine de l'espèce Trypanosoma. L'invention concerne en outre des procédés d'inhibition de ladite protéine pour le traitement d'infections protozoaires, la malaria et la surra, par la Geldanamycine et la 17-AAG. L'invention concerne également des procédés d'identification de ces inhibitions, des compositions et des méthodes de traitement desdites infections. Pour finir, la présente invention concerne également l'examen de l'efficacité d'un inhibiteur de Hsp90 comme agents anti-malaria et anti-surra.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)