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1. (WO2011154140) PROCESS FOR THE PREPARATION OF N- [2 - (7 -METHOXY - 1 - NAPHTHYL) - ETHYL] ACETAMIDE AND NEW CRYSTALLINE FORM
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/154140    International Application No.:    PCT/EP2011/002834
Publication Date: 15.12.2011 International Filing Date: 09.06.2011
IPC:
C07C 217/74 (2006.01), C07C 233/18 (2006.01), C07C 255/37 (2006.01)
Applicants: GADOR S.A. [AR/AR]; Darwin 429 1414 Buenos Aires (AR) (For All Designated States Except US).
CONICET -CONSEJO NAC. DE INVESTIGACIONES CIENTÍFICAS Y TÉCNICAS [AR/AR]; Rivadavia 1917 C1033 Buenos Aires (AR) (For All Designated States Except US).
TOMBARI, Dora, Graciela [AR/AR]; (AR) (For US Only).
MANGONE, Constanza, Pia [AR/AR]; (AR) (For US Only).
GARCIA, Maria, Beatriz [AR/AR]; (AR) (For US Only).
VECCHIOLI, Adriana [IT/AR]; (AR) (For US Only).
LABRIOLA, Rafael, Alberto [AR/AR]; (AR) (For US Only).
BURTON, Gerardo [AR/AR]; (AR) (For US Only).
RUSTOY, Eduardo, Miguel [AR/AR]; (AR) (For US Only)
Inventors: TOMBARI, Dora, Graciela; (AR).
MANGONE, Constanza, Pia; (AR).
GARCIA, Maria, Beatriz; (AR).
VECCHIOLI, Adriana; (AR).
LABRIOLA, Rafael, Alberto; (AR).
BURTON, Gerardo; (AR).
RUSTOY, Eduardo, Miguel; (AR)
Agent: WINKLER, Andreas; Boehmert & Boehmert Hollerallee 32 28209 Bremen (DE)
Priority Data:
61/353,266 10.06.2010 US
Title (EN) PROCESS FOR THE PREPARATION OF N- [2 - (7 -METHOXY - 1 - NAPHTHYL) - ETHYL] ACETAMIDE AND NEW CRYSTALLINE FORM
(FR) NOUVEAU PROCÉDÉ DE PRÉPARATION DE N-[2-(7-MÉTHOXY-1-NAPHTYL)-ÉTHYL]ACÉTAMIDE ET NOUVELLE FORME CRISTALLINE
Abstract: front page image
(EN)A novel process for the preparation of N-[2-(7-methoxy-1-naphthyl)ethyl]acetamide, also known as agomelatine, Compound (I), from 7-methoxy-tetralone as starting material, and to a new crystalline form X of agomelatine.
(FR)L'invention concerne un nouveau procédé de préparation de N-[2-(7-méthoxy-1-naphtyl)éthyl]acétamide, également appelé agomélatine, le composé (I), à partir de 7-méthoxy-tétralone comme matière première, et une nouvelle forme cristalline X d'agomélatine.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)