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1. (WO2011154007) BACTERIOPHAGES FOR USE AGAINST BACTERIAL INFECTIONS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/154007    International Application No.:    PCT/DK2011/050201
Publication Date: 15.12.2011 International Filing Date: 08.06.2011
IPC:
A61K 35/76 (2006.01), A61P 31/04 (2006.01)
Applicants: ROBERT, Leah [DK/DK]; (DK)
Inventors: ROBERT, Leah; (DK)
Agent: RASMUSSEN RAVN, Torben; Awapatent A/S Rigensgade 11 DK-1316 København K (DK)
Priority Data:
PA 2010 00492 08.06.2010 DK
Title (EN) BACTERIOPHAGES FOR USE AGAINST BACTERIAL INFECTIONS
(FR) BACTÉRIOPHAGES DESTINÉS À ÊTRE UTILISÉS CONTRE DES INFECTIONS BACTÉRIENNES
Abstract: front page image
(EN)The present invention relates to a composition comprising obligate lytic bacteriophages generated by a method comprising subjecting normally in vivo lysogenic, pseudolysogenic or temperate bacteriophages to genetic modifications in vitro, which alters the biological activity of one or more of the individual gene products for establishing, maintaining, controlling or regulating the lysogenic life cycle of the bacteriophages, thereby converting them to obligate lytic bacteriophages, wherein the genetic modification includes modification of a single gene in the operon containing a gene resulting in a gene product for establishing, maintaining, controlling or regulating the lysogenic life cycle of the bacteriophages.
(FR)La présente invention concerne une composition comprenant des bactériophages lytiques stricts produits par un procédé comprenant la soumission de bactériophages normalement lysogéniques, pseudolysogéniques ou tempérés in vivo à des modifications génétiques in vitro, qui changent l'activité biologique d'un ou de plusieurs des produits de gène individuels pour établir, maintenir, contrôler ou réguler le cycle de vie lysogénique des bactériophages, en les convertissant ainsi en bactériophages lytiques stricts, la modification génétique comprenant la modification d'un seul gène dans l'opéron contenant un gène qui donne un produit de gène permettant d'établir, de maintenir, de contrôler ou de réguler le cycle de vie lysogénique des bactériophages.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)