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1. WO2011154004 - A PHARMACEUTICAL SPRAY COMPOSITION COMPRISING A VITAMIN D ANALOGUE AND A CORTICOSTEROID

Publication Number WO/2011/154004
Publication Date 15.12.2011
International Application No. PCT/DK2011/000060
International Filing Date 10.06.2011
IPC
A61K 9/12 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
10Dispersions; Emulsions
12Aerosols; Foams
A61K 47/06 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
A61K 47/10 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
08containing oxygen
10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols ; Poloxamers; PEG/POE alkyl ethers
A61K 9/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
CPC
A61K 31/573
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives, e.g. steroids
57substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane, progesterone
573substituted in position 21, e.g. cortisone, dexamethasone, prednisone ; or aldosterone
A61K 31/58
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives, e.g. steroids
58containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
A61K 31/59
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
59Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
A61K 31/593
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
59Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
5939,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
A61K 47/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
A61K 47/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
08containing oxygen, ; e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
Applicants
  • LEO PHARMA A/S [DK]/[DK] (AllExceptUS)
  • LIND, Marianne [DK]/[DK] (UsOnly)
  • RASMUSSEN, Gritt [DK]/[DK] (UsOnly)
  • SONNE, Mette Rydahl [DK]/[DK] (UsOnly)
  • HANSEN, Jens [DK]/[DK] (UsOnly)
  • PETERSSON, Karsten [DK]/[DK] (UsOnly)
Inventors
  • LIND, Marianne
  • RASMUSSEN, Gritt
  • SONNE, Mette Rydahl
  • HANSEN, Jens
  • PETERSSON, Karsten
Agents
  • THALSØ-MADSEN, Birgit
Priority Data
61/353,89311.06.2010US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) A PHARMACEUTICAL SPRAY COMPOSITION COMPRISING A VITAMIN D ANALOGUE AND A CORTICOSTEROID
(FR) COMPOSITION PHARMACEUTIQUE POUR AÉROSOL COMPRENANT UN ANALOGUE DE VITAMINE D ET UN CORTICOSTÉROÏDE
Abstract
(EN)
The present invention relates to a topical spray composition comprising a biologically active vitamin D derivative and a corticosteroid, and its use in the treatment of dermal diseases and conditions. The spray comprises especially a propellant selected freom the group consisting of dimethyl ether, diethyl ether and methylethyl ether or a mixture thereof and further a pharmaceutically acceptable lipid carrier solubilised or suspended in said propellant.
(FR)
La présente invention concerne une composition topique d'aérosol qui comprend un dérivé de vitamine D biologiquement actif et un corticostéroïde, et concerne également son utilisation dans le traitement de maladies et d'affections dermiques. Ledit aérosol comprend en particulier un propulseur sélectionné dans le groupe constitué par l'éther diméthylique, l'éther diéthylique et l'éther méthyléthylique ou un mélange de ceux-ci, ainsi qu'un vecteur de lipide pharmaceutiquement acceptable solubilisé ou en suspension dans ledit propulseur.
Latest bibliographic data on file with the International Bureau