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Pub. No.:    WO/2011/153639    International Application No.:    PCT/CA2011/050347
Publication Date: 15.12.2011 International Filing Date: 07.06.2011
A61N 5/10 (2006.01), A61N 5/00 (2006.01)
Applicants: THE UNIVERSITY OF MANITOBA [CA/CA]; 631 Drake Centre Winnipeg, Manitoba R3T 5V4 (CA) (For All Designated States Except US).
FIEGE, Jason [CA/CA]; (CA) (For US Only).
MCCURDY, Boyd [CA/CA]; (CA) (For US Only).
POTREBKO, Peter [CA/CA]; (CA) (For US Only).
CULL, Andrew [CA/CA]; (CA) (For US Only).
CHAMPION, Heather [CA/CA]; (CA) (For US Only).
BERZISH, Murphy [CA/CA]; (CA) (For US Only)
Inventors: FIEGE, Jason; (CA).
MCCURDY, Boyd; (CA).
POTREBKO, Peter; (CA).
CULL, Andrew; (CA).
CHAMPION, Heather; (CA).
BERZISH, Murphy; (CA)
Agent: BATTISON WILLIAMS DUPUIS; 2157 Henderson Hwy Winnipeg, Manitoba R2G 1P9 (CA)
Priority Data:
61/352,091 07.06.2010 US
Abstract: front page image
(EN)A novel and powerful fluence and beam orientation optimization package for radiotherapy optimization, called PARETO (Pareto-Aware Radiotherapy Evolutionary Treatment Optimization), makes use of a multi-objective genetic algorithm capable of optimizing several objective functions simultaneously and mapping the structure of their trade-off surface efficiently and in detail. PARETO generates a database of Pareto non-dominated solutions and allows the graphical exploration of trade-offs between multiple planning objectives during IMRT treatment planning. PARETO offers automated and truly multi-objective treatment plan optimization, which does not require any objective weights to be chosen, and therefore finds a large sample of optimized solutions defining a trade-off surface, which represents the range of compromises that are possible.
(FR)L'invention concerne une nouvelle et puissante fluence et un progiciel d'optimisation d'orientation de faisceau pour optimisation de radiothérapie, appelé PARETO (optimisation de traitement évolutif de radiothérapie compatible avec PARETO) utilisant un algorithme génétique multi-objectif capable d'optimiser simultanément plusieurs fonctions d'objectif et de mapper la structure de leur surface de compromis efficacement et en détail. PARETO génère une base de données de solutions Pareto non dominantes et permet l'exploration graphique de compromis entre de multiples objectifs de planification pendant la planification d'un traitement IMRT. PARETO offre une optimisation de plan de traitement multi-objectif automatique et authentique qui ne nécessite pas de choisir les poids d'objectifs quelconques, et trouve donc un large échantillon de solutions optimisées définissant une surface de compromis qui représente la gamme des compromis possibles.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)