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Pub. No.:    WO/2011/153138    International Application No.:    PCT/US2011/038548
Publication Date: 08.12.2011 International Filing Date: 31.05.2011
C07D 471/04 (2006.01)
Applicants: INTRA-CELLULAR THERAPIES, INC. [US/US]; 3690 Broadway New York, New York 10032 (US) (For All Designated States Except US).
LI, Peng [CN/US]; (US) (For US Only).
ZHENG, Hailin [CN/US]; (US) (For US Only).
ZHAO, Jun [CN/US]; (US) (For US Only).
WENNOGLE, Lawrence P. [US/US]; (US) (For US Only)
Inventors: LI, Peng; (US).
ZHENG, Hailin; (US).
ZHAO, Jun; (US).
WENNOGLE, Lawrence P.; (US)
Agent: LA, Brittany; Hoxie & Associates LLC 75 Main Street Suite 301 Millburn, New Jersey 07041 (US)
Priority Data:
61/349,960 31.05.2010 US
Abstract: front page image
(EN)Optionally substituted (1- or 3-oxy)-4,5,7,8-tetrahydro-(optionally 4-oxo, 4-thioxo or 4-imino)-2H-imidazo[1,2-a]pyrrolo[3,4-e]pyrimidine or (1- or 3-oxy)-4,5,7,8,9-pentahydro-(optionally 4-oxo, 4-thioxo or 4-imino)-2H-pyrimido[1,2-a]pyrrolo[3,4-e]pyrimidine compounds, processes for their production, their use as pharmaceuticals and pharmaceutical compositions comprising the same.
(FR)L'invention concerne des composés (1- ou 3-oxy)-4,5,7,8-tétrahydro-(éventuellement 4-oxo, 4-thioxo ou 4-imino)-2H-imidazo[1,2-a]pyrrolo[3,4-e]pyrimidines ou (1- ou 3-oxy)-4,5,7,8,9-pentahydro-(éventuellement 4-oxo, 4-thioxo ou 4-imino)-2H-pyrimido[1,2-a]pyrrolo[3,4-e]pyrimidines éventuellement substitués, des procédés pour leur fabrication, leur utilisation en tant que produits pharmaceutiques et des compositions pharmaceutiques les comportant.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)