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Machine translation
1. (WO2011152798) METHOD FOR INDUCING PLURIPOTENCY IN HUMAN SOMATIC CELLS WITH PRDM14 OR NFRKB
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/152798    International Application No.:    PCT/SG2011/000202
Publication Date: 08.12.2011 International Filing Date: 02.06.2011
IPC:
C12N 5/071 (2010.01), C12N 5/074 (2010.01), C12N 5/0735 (2010.01), C12N 5/10 (2006.01)
Applicants: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH [SG/SG]; 1 Fusionopolis Way #20-10, Connexis Singapore 138632 (SG) (For All Designated States Except US).
NG, Huck, Hui [SG/SG]; (SG) (For US Only).
CHIA, Na, Yu [SG/SG]; (SG) (For US Only).
FENG, Bo [CN/SG]; (SG) (For US Only)
Inventors: NG, Huck, Hui; (SG).
CHIA, Na, Yu; (SG).
FENG, Bo; (SG)
Agent: YU SARN AUDREY & PARTNERS; 24 Raffles Place #27-01 Clifford Centre Singapore 048621 (SG)
Priority Data:
61/350,843 02.06.2010 US
Title (EN) METHOD FOR INDUCING PLURIPOTENCY IN HUMAN SOMATIC CELLS WITH PRDM14 OR NFRKB
(FR) PROCÉDÉ D'INDUCTION DE PLURIPOTENCE DANS CELLULES SOMATIQUES HUMAINES PAR PRDM14 OU NFRKB
Abstract: front page image
(EN)Methods of inducing pluripotency in human somatic cells and methods of maintaining pluripotency in human embryonic stem cells (hESCs) are provided, as well as cells and uses of employing such cells. The methods comprise culturing cells in the presence of (i) OCT4 and SOX2; (ii) at least one of KLF4 and c-MYC; and at least one of PRDM14 and NFRKB.
(FR)L'invention concerne des procédés d'induction de la pluripotence dans des cellules somatiques humaines et des procédés de maintien de la pluripotence dans des cellules souches embryonnaires humaines (hESC) ainsi que des cellules et des utilisations de telles cellules. Les procédés comprennent la mise en culture de cellules en présence (i) de OCT4 et SOX2 ; et (ii) de KLF4 et/ou c-MYC, et de PRDM14 et/ou NFRKB.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)