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Pub. No.:    WO/2011/151259    International Application No.:    PCT/EP2011/058713
Publication Date: 08.12.2011 International Filing Date: 27.05.2011
C07D 487/04 (2006.01), A61K 31/4985 (2006.01)
Applicants: BAYER INTELLECTUAL PROPERTY GMBH [DE/DE]; Alfred-Nobel-Strasse 10 40789 Monheim (DE) (For All Designated States Except US).
KLAR, Ulrich [DE/DE]; (DE) (For US Only).
KOPPITZ, Marcus [DE/DE]; (DE) (For US Only).
JAUTELAT, Rolf [DE/DE]; (DE) (For US Only).
KOSEMUND, Dirk [DE/DE]; (DE) (For US Only).
BOHLMANN, Rolf [DE/DE]; (DE) (For US Only).
BADER, Benjamin [DE/DE]; (DE) (For US Only).
LIENAU, Philip [DE/DE]; (DE) (For US Only).
SIEMEISTER, Gerhard [DE/DE]; (DE) (For US Only).
SCOTT, William [US/DE]; (DE) (For US Only)
Inventors: KLAR, Ulrich; (DE).
KOPPITZ, Marcus; (DE).
BADER, Benjamin; (DE).
LIENAU, Philip; (DE).
SIEMEISTER, Gerhard; (DE).
SCOTT, William; (DE)
BAYER INTELLECTUAL PROPERTY GMBH; Creative Campus Monheim Alfred-Nobel-Strasse 10 40789 Monheim (DE)
Priority Data:
10164587.7 01.06.2010 EP
Abstract: front page image
(EN)The present invention relates to substituted imidazopyrazine compounds of general formula (I) in which A, R1, R3 and R5 are as given in the description and in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds, to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, as well as to intermediate compounds useful in the preparation of said compounds.
(FR)La présente invention porte sur des composés imidazopyrazines substituées de formule générale (I) dans laquelle A, R1, R3 et R5 sont tels que définis dans la description et dans les revendications, sur des procédés de préparation desdits composés, sur des compositions et combinaisons pharmaceutiques comprenant lesdits composés, sur l'utilisation desdits composés pour la préparation d'une composition pharmaceutique destinée au traitement ou à la prophylaxie d'une maladie, ainsi que sur des composés intermédiaires utiles pour la préparation desdits composés.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)