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1. (WO2011150517) XYXIN FRAGMENT BIOMARKER FOR DIAGNOSIS OF COLON CANCER
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/150517    International Application No.:    PCT/CA2011/050330
Publication Date: 08.12.2011 International Filing Date: 01.06.2011
IPC:
C07K 14/47 (2006.01), A61K 38/17 (2006.01), A61P 35/00 (2006.01), G01N 33/48 (2006.01), G01N 33/483 (2006.01), G01N 33/574 (2006.01), G01N 33/68 (2006.01)
Applicants: MIRACULINS, INC. [CA/CA]; 6-1250 Waverley St. Winnipeg, Manitoba R3T 6C6 (CA) (For All Designated States Except US).
BARKER, Douglas [CA/CA]; (CA) (For US Only).
ATNIKOV, Katrin [CA/CA]; (CA) (For US Only).
ZHANG, Yilan [CA/CA]; (CA) (For US Only).
FROST, Stephen [US/US]; (US) (For US Only)
Inventors: BARKER, Douglas; (CA).
ATNIKOV, Katrin; (CA).
ZHANG, Yilan; (CA).
FROST, Stephen; (US)
Agent: RIDOUT & MAYBEE LLP; 225 King Street West 10th Floor Toronto, Ontario M5V 3M2 (CA)
Priority Data:
61/350,195 01.06.2010 US
Title (EN) XYXIN FRAGMENT BIOMARKER FOR DIAGNOSIS OF COLON CANCER
(FR) BIOMARQUEUR POUR LE DIAGNOSTIC ET LE TRAITEMENT DU CANCER COLORECTAL
Abstract: front page image
(EN)The present invention relates to the field of the diagnosis of large intestine/colon diseases. More particularly, the present invention provides a method for differential diagnosis of colorectal cancer from a non-malignant disease of the large intestine/colon, and from a healthy large intestine/colon. The invention also relates to treatment of colorectal cancer. The peptide fragment, consisting of amino acids 62 to 110 of human Xyxin, was found to be significantly down regulated in serum samples obtained from colorectal cancer populations, as compared to serum samples obtained from healthy control populations and benign disease populations.
(FR)La présente invention se rapporte au domaine du diagnostic des maladies du gros intestin ou du côlon. Elle concerne plus particulièrement un procédé de diagnostic différentiel du cancer colorectal à partir d'une maladie non maligne du gros intestin ou du colon, et à partir d'un gros intestin ou d'un côlon sain. L'invention concerne en outre le traitement du cancer colorectal.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)