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1. (WO2011150453) DIAGNOSTIC, PROGNOSTIC AND THERAPEUTIC USE OF A LONG NON-CODING RNA
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/150453    International Application No.:    PCT/AU2011/000657
Publication Date: 08.12.2011 International Filing Date: 01.06.2011
IPC:
C12N 15/113 (2010.01), A61K 31/713 (2006.01), A61P 35/00 (2006.01), C07K 16/30 (2006.01), G01N 33/50 (2006.01), G01N 33/574 (2006.01)
Applicants: THE UNIVERSITY OF QUEENSLAND [AU/AU]; St Lucia, Queensland 4072 (AU) (For All Designated States Except US).
MATTICK, John Stanley [AU/AU]; (AU) (For US Only).
DINGER, Marcel Eduard [AU/AU]; (AU) (For US Only).
ASKARIAN-AMIRI, Marjan Effat [NZ/AU]; (AU) (For US Only)
Inventors: MATTICK, John Stanley; (AU).
DINGER, Marcel Eduard; (AU).
ASKARIAN-AMIRI, Marjan Effat; (AU)
Agent: FISHER ADAMS KELLY; Level 29 12 Creek Street Brisbane, Queensland 4000 (AU)
Priority Data:
61/350,106 01.06.2010 US
Title (EN) DIAGNOSTIC, PROGNOSTIC AND THERAPEUTIC USE OF A LONG NON-CODING RNA
(FR) UTILISATION EN DIAGNOSTIC, PRONOSTIC ET THÉRAPEUTIQUE D'UN LONG ARN NON CODANT
Abstract: front page image
(EN)In alternative embodiments, this invention relates to the use of a long non-coding anti-sense RNA for the diagnosis, prognosis and therapy of cancer, including breast cancer. The invention also relates to the design and production of therapeutic agents that modulate ZFAS1 expression and/or activity. The therapeutic agents may be used to modulate abnormal cell proliferation and/or alleviate symptoms associated with the development and/or progression of cancer.
(FR)Dans divers modes de réalisation, cette invention concerne l'utilisation d'un long ARN antisens non codant pour le diagnostic, le pronostic et la thérapie du cancer, notamment le cancer de sein. Cette invention concerne également la conception et la production d'agents thérapeutiques qui modulent l'expression et/ou l'activité de ZFAS1. Les agents thérapeutiques peuvent être utilisés pour moduler une prolifération cellulaire anormale et/ou atténuer les symptômes associés au développement et/ou à la progression du cancer.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)