A system, method, and a computer program product for interactive communication are provided. An individual can be discharged from a medical facility. At least one discharge instruction tailored to at least one condition of the individual can be generated. At least one discharge instruction can include information concerning follow up care for the individual. At least one communication to the individual can be generated. The individual can be requested to respond to at least one communication and indicate a condition of the individual. Based on a response by the individual, an instruction to the individual concerning at least one treatment option for the individual can be generated.