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1. (WO2011150008) ANTIBODIES TO HUMAN GDF8
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/150008    International Application No.:    PCT/US2011/037837
Publication Date: 01.12.2011 International Filing Date: 25.05.2011
IPC:
C07K 16/22 (2006.01), A61K 39/395 (2006.01), A61P 3/00 (2006.01), A61P 21/00 (2006.01)
Applicants: REGENERON PHARMACEUTICALS, INC. [US/US]; 777 Old Saw Mill River Road Tarrytown, NY 10591 (US) (For All Designated States Except US).
STITT, Trevor [US/US]; (US) (For US Only).
LATRES, Esther [US/US]; (US) (For US Only)
Inventors: STITT, Trevor; (US).
LATRES, Esther; (US)
Agent: COTTINGHAM, Frank; Regeneron Pharmaceuticals, Inc. 777 Old Saw Mill River Road Tarrytown, NY 10591 (US)
Priority Data:
61/348,559 26.05.2010 US
61/372,882 12.08.2010 US
Title (EN) ANTIBODIES TO HUMAN GDF8
(FR) ANTICORPS ANTI-GDF8 HUMAIN
Abstract: front page image
(EN)The present invention provides isolated human or humanized antibodies or antigen- binding fragments thereof which specifically bind to Growth and Differentiation Factor-8 (GDF8) and block GDF8 activity. The antibodies and antibody fragments of the present invention may be used in therapeutic methods for treating conditions or disorders which are ameliorated or improved by inhibition of GDF8.
(FR)L'invention concerne des anticorps humains ou humanisés isolés ou des fragments de liaison de ceux-ci qui se lient spécifiquement au facteur-8 de croissance et de différenciation (GDF8) et bloquent l'activité de GDF8. Les anticorps et les fragments d'anticorps de l'invention peuvent être utilisés dans des méthodes thérapeutiques pour traiter des états ou des troubles qui sont améliorés ou soulagés par inhibition de GDF8.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)