WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2011149964) METHODS FOR TREATING OR PREVENTING VASCULAR GRAFT FAILURE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/149964    International Application No.:    PCT/US2011/037776
Publication Date: 01.12.2011 International Filing Date: 24.05.2011
IPC:
A61K 38/00 (2006.01)
Applicants: MOERAE MATRIX, INC., [US/US]; 31 River Road Highland Park, NJ 08904 (US) (For All Designated States Except US).
LANDER, Cynthia [US/US]; (US).
PANITCH, Alyssa [US/US]; (US).
BROPHY, Colleen [US/US]; (US).
SEAL, Brandon [US/US]; (US)
Inventors: LANDER, Cynthia; (US).
PANITCH, Alyssa; (US).
BROPHY, Colleen; (US).
SEAL, Brandon; (US)
Agent: LUBIT, Beverly, W.; C/o Greenberg Traurig, LLP 200 Park Avenue Florham Park, NJ 07932 (US)
Priority Data:
61/347,495 24.05.2010 US
Title (EN) METHODS FOR TREATING OR PREVENTING VASCULAR GRAFT FAILURE
(FR) PROCÉDÉ DE TRAITEMENT OU DE PRÉVENTION D'UNE RUPTURE DE GREFFE VASCULAIRE
Abstract: front page image
(EN)The described invention provides pharmaceutical compositions and methods for treating or preventing vascular graft failure in a subject in need of such treatment, the method comprising administering a therapeutically effective amount of a composition comprising a polypeptide of amino acid sequence YARAAARQARAKALARQLGVAA (SEQ ID NO: 1) or a functional equivalent thereof, and a pharmaceutically acceptable carrier. The methods also are clinically useful for treating a pre-atherosclerotic intimal hyperplasia condition.
(FR)La présente invention concerne des compositions pharmaceutiques et des procédés de traitement ou de prévention d'une rupture de greffe vasculaire chez un patient nécessitant un tel traitement, le procédé comprenant l'administration d'une quantité thérapeutiquement efficace d'une composition comprenant un polypeptide de séquence d'acides aminés YARAAARQARAKALARQLGVAA (SEQ ID NO : 1) ou un équivalent fonctionnel de celui-ci, et un vecteur pharmaceutiquement acceptable. Les procédés sont également utiles sur le plan clinique pour le traitement d'une condition d'hyperplasie intimale athérosclérotique.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)