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1. (WO2011149917) STABILIZED AMYLOID- β OLIGOMERS AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/149917    International Application No.:    PCT/US2011/037711
Publication Date: 01.12.2011 International Filing Date: 24.05.2011
IPC:
C07K 1/00 (2006.01)
Applicants: ADLYFE, INC. [US/US]; 9430 Key West Ave., Suite 210 Rockville, MD 20850 (US) (For All Designated States Except US).
DUAN, Roxanne [US/US]; (US) (For US Only).
MOLL, Jonathan [US/US]; (US) (For US Only).
RUDOLPH, Alan, S. [US/US]; (US) (For US Only)
Inventors: DUAN, Roxanne; (US).
MOLL, Jonathan; (US).
RUDOLPH, Alan, S.; (US)
Agent: BRINCKERHOFF, Courtenay, C.; Foley & Lardner LLP 3000 K Street, N.W. Washington, DC 20007-5143 (US)
Priority Data:
61/348,186 25.05.2010 US
61/396,378 25.05.2010 US
Title (EN) STABILIZED AMYLOID- β OLIGOMERS AND USES THEREOF
(FR) OLIGOMÈRES Β-AMYLOÏDES STABILISÉS ET LEURS UTILISATIONS
Abstract: front page image
(EN)The present invention pertains to stabilized Αβ oligomer compositions. Methods for generating stabilized Αβ oligomer compounds are also provided herein. Additionally, screening assays employing the Αβ oligomer compounds and methods for generating therapeutics with the Αβ oligomers are also provided. In a particular embodiment, the Αβ oligomer described herein is comprised of Αβ42 peptide.
(FR)La présente invention concerne des compositions d'oligomères β-amyloïdes stabilisés. L'invention concerne également des procédés de production de composés d'oligomères β-amyloïdes stabilisés. L'invention concerne, en outre, des tests de dépistage utilisant lesdits composés d'oligomères β-amyloïdes et des procédés de production de médicaments à base desdits oligomères β-amyloïdes. Dans un mode de réalisation particulier, l'oligomère β-amyloïde décrit ici est constitué du peptide Aβ42.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)