WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2011149878) AN AMINOPYRAZOLE TRIAZOLOTHIADIAZOLE INHIBITOR OF C-MET PROTEIN KINASE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/149878    International Application No.:    PCT/US2011/037659
Publication Date: 01.12.2011 International Filing Date: 24.05.2011
IPC:
C07D 513/04 (2006.01), A61K 31/4709 (2006.01), A61P 35/00 (2006.01)
Applicants: VERTEX PHARMACEUTICALS INCORPORATED [US/US]; 130 Waverly Street Cambridge, MA 02139 (US) (For All Designated States Except US).
LAUFFER, David, J. [US/US]; (US) (For US Only).
LI, Pan [US/US]; (US) (For US Only).
ROEPER, Stefanie [US/CH]; (US) (For US Only).
IBRAHIM, Shereen [US/US]; (US) (For US Only).
KULDIPKUMAR, Anuj, K. [IN/US]; (US) (For US Only).
SHI, Yi [US/US]; (US) (For US Only).
MILLER, David, B., Jr. [US/US]; (US) (For US Only)
Inventors: LAUFFER, David, J.; (US).
LI, Pan; (US).
ROEPER, Stefanie; (US).
IBRAHIM, Shereen; (US).
KULDIPKUMAR, Anuj, K.; (US).
SHI, Yi; (US).
MILLER, David, B., Jr.; (US)
Agent: PEARSON, Daniel, A.; Vertex Pharmaceuticals Incorporated 130 Waverly Street Cambridge, MA 02139 (US)
Priority Data:
61/348,929 27.05.2010 US
Title (EN) AN AMINOPYRAZOLE TRIAZOLOTHIADIAZOLE INHIBITOR OF C-MET PROTEIN KINASE
(FR) AMINOPYRAZOLE-TRIAZOLOTHIADIAZOLE INHIBITEUR DE LA PROTÉINE KINASE C-MET
Abstract: front page image
(EN)The present invention relates to anhydrous and hydrated forms of Compound 1, which are useful in the inhibition of c-Met protein kinase. The invention also provides pharmaceutically acceptable compositions comprising compounds of formula I and methods of using the compositions in the treatment of proliferative disorders.
(FR)La présente invention concerne les formes anhydre et hydratée du composé 1, qui sont utiles dans l'inhibition de la protéine kinase c-Met. L'invention concerne également des compositions de qualité pharmaceutique qui comportent des composés de la formule I, ainsi que des procédés d'utilisation des compositions dans le traitement de troubles prolifératifs.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)