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1. (WO2011149493) SINGLE -CHAIN VARIABLE FRAGMENT ANTI-CD133 ANTIBODIES AND USES THEREOF

Pub. No.:    WO/2011/149493    International Application No.:    PCT/US2010/059827
Publication Date: Dec 1, 2011 International Filing Date: Dec 10, 2010
IPC: C07K 16/28
A61K 39/395
C07K 16/30
C07K 19/00
G01N 33/53
Applicants: REGENTS OF THE UNVIVERSITY OF MINNESOTA
OHLFEST, John, R.
PANYAM, Jayanth
SWAMINATHAN, Suresh, Kumar
VALLERA, Daniel, A.
Inventors: OHLFEST, John, R.
PANYAM, Jayanth
SWAMINATHAN, Suresh, Kumar
VALLERA, Daniel, A.
Title: SINGLE -CHAIN VARIABLE FRAGMENT ANTI-CD133 ANTIBODIES AND USES THEREOF
Abstract:
Disclosed herein are a monoclonal antibody that specifically binds to human CD 133 and single-chain variable fragments thereof. Also disclosed herein is a hybridoma that produces the monoclonal antibody that specifically binds to human CD133.