Search International and National Patent Collections

1. (WO2011148800) METHOD AND DEVICE FOR OPTIMIZATION RADIOTHERAPY PARTICLE BEAMS

Pub. No.:    WO/2011/148800    International Application No.:    PCT/JP2011/061113
Publication Date: Dec 1, 2011 International Filing Date: May 9, 2011
IPC: A61N 5/10
Applicants: MITSUBISHI ELECTRIC CORPORATION
MITSUBISHI ELECTRIC RESEARCH LABORATORIES, INC.
BRAND, Matthew
Inventors: BRAND, Matthew
Title: METHOD AND DEVICE FOR OPTIMIZATION RADIOTHERAPY PARTICLE BEAMS
Abstract:
Radiation doses are optimized by providing a model of the set of beams and a target dose in normalized forms. A Gram matrix is determined from the model. The target dose is subsampled to determine initial intensity values for the set of beams. Then, the following steps are iterated until convergence. A very small positive value, 0 < ε<< 1, is added to each intensity value to ensure the intensity value is greater than zero. Each intensity value is multiplied by the Gram matrix to determine a product, which is divided element-wise into the normalized target dose to determine corresponding ratios. If the ratios are all close to 1, within a numerical error tolerance, the intensity values of the set of beam are output. Otherwise, the intensity values are multipled by the ratios before a next iteration.