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Machine translation
1. (WO2011148392) PROCESS FOR THE PREPARATION OF (2S,4S,5S,7S)-N-(2-CARBAMYL-2- METHYLPROPYL)-5-AMINO-4-HYDROXY-2,7-DIISOPROPYL-8-[4-METHOXY-3-(3- METHOXYPROPOXY)PHENYL]-OCTANAMIDE HEMIFUMARATE AND ITS INTERMEDIATES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/148392    International Application No.:    PCT/IN2011/000366
Publication Date: 01.12.2011 International Filing Date: 26.05.2011
IPC:
C07C 231/02 (2006.01), C07C 247/12 (2006.01), C07D 207/32 (2006.01), C07D 303/40 (2006.01)
Applicants: MSN LABORATORIES LIMITED [IN/IN]; Sy. No: 317 & 323 Rudraram (Vil) Patancheru (Mdl), Medak (Dist) Hyderabad 502 329 Andhra Pradesh (IN) (For All Designated States Except US).
SATYANARAYANA REDDY, Manne [IN/IN]; (IN) (For US Only).
THIRUMALAI RAJAN, Srinivasan [IN/IN]; (IN) (For US Only).
ESWARAIAH, Sajja [IN/IN]; (IN) (For US Only).
VENKAT REDDY, Ghojala [IN/IN]; (IN) (For US Only).
RAMA SUBBA REDDY, Karamala [IN/IN]; (IN) (For US Only).
SAHADEVA REDDY, Maramreddy [IN/IN]; (IN) (For US Only)
Inventors: SATYANARAYANA REDDY, Manne; (IN).
THIRUMALAI RAJAN, Srinivasan; (IN).
ESWARAIAH, Sajja; (IN).
VENKAT REDDY, Ghojala; (IN).
RAMA SUBBA REDDY, Karamala; (IN).
SAHADEVA REDDY, Maramreddy; (IN)
Common
Representative:
THIRUMALAI RAJAN, Srinivasan; Sy. No: 317 & 323 Rudraram (Vil) Patancheru (Mdl), Medak (Dist) Hyderabad 502 329 Andhra Pradesh (IN)
Priority Data:
1467/CHE/2010 28.05.2010 IN
1468/CHE/2010 28.05.2010 IN
1735/CHE/2011 23.05.2011 IN
Title (EN) PROCESS FOR THE PREPARATION OF (2S,4S,5S,7S)-N-(2-CARBAMYL-2- METHYLPROPYL)-5-AMINO-4-HYDROXY-2,7-DIISOPROPYL-8-[4-METHOXY-3-(3- METHOXYPROPOXY)PHENYL]-OCTANAMIDE HEMIFUMARATE AND ITS INTERMEDIATES THEREOF
(FR) PROCÉDÉ POUR PRÉPARER UN HÉMIFUMARATE DU COMPOSÉ (2S,4S,5S,7S)-N-(2-CARBAMOYL-2- MÉTHYLPROPYL)-5-AMINO-4-HYDROXY-2,7-DIISOPROPYL-8-[4-MÉTHOXY-3-(3- MÉTHOXYPROPOXY)PHÉNYL]-OCTANAMIDE ET PRODUITS INTERMÉDIAIRES CORRESPONDANTS
Abstract: front page image
(EN)The present invention relates to a process for the preparation of (2S,4S,5S,7S)-N-(2- Carbamoyl-2-methylpropyl)-5-amino-4-hydroxy-2,7-diisopropyl-8-[4-methoxy-3-(3-methoxy propoxy )phenyl]-octanamide compound of formula- 1 and its pharmaceutically acceptable salts thereof. Further, relates to the processes for the preparation of (R)-4-(2-(halomethyl)-3- methylbutyl)-l-methoxy-2-(3-methoxypropoxy) benzene and (R)-2-(4-methoxy-3-(3-methoxy propoxy) benzyl)-3-methyIbutan-l-ol useful intermediates in the synthesis of compound of formula- 1.
(FR)L'invention concerne un procédé pour préparer un composé (2S,4S,5S,7S)-N-(2- carbamoyl-2-méthylpropyl)-5-amino-4-hydroxy-2,7-diisopropyl-8-[4-méthoxy-3-(3-méthoxy propoxy )phényl]-octanamide de formule (1) et ses sels pharmaceutiquement acceptables. Cette invention concerne en outre des procédés pour préparer du (R)-4-(2-(halométhyl)-3- méthylbutyl)-1-méthoxy-2-(3-méthoxypropoxy) benzène et du (R)-2-(4-méthoxy-3-(3-méthoxy propoxy) benzyl)-3-méthyIbutan-1-ol qui sont des produits intermédiaires utiles pour synthétiser ledit composé de formule (1).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)