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Machine translation
1. (WO2011147038) HETEROCYCLYL-PYRIDINYL-BASED BIPHOSPHONIC ACID, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, COMPOSITION THEREOF AND METHOD OF USE THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/147038    International Application No.:    PCT/CA2011/050322
Publication Date: 01.12.2011 International Filing Date: 27.05.2011
IPC:
C07F 9/6558 (2006.01), A61K 31/675 (2006.01), A61P 19/10 (2006.01), A61P 3/06 (2006.01), A61P 31/12 (2006.01), A61P 35/00 (2006.01), C07F 9/58 (2006.01)
Applicants: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY [CA/CA]; 845 Sherbrooke Street West Montreal, Québec H3A 2T5 (CA) (For All Designated States Except US).
TSANTRIZOS, Youla, S. [CA/CA]; (CA) (For US Only).
DE SCHUTTER, Joris, Wim [BE/CA]; (CA) (For US Only).
LIN, Yih-Shyan [CA/CA]; (CA) (For US Only)
Inventors: TSANTRIZOS, Youla, S.; (CA).
DE SCHUTTER, Joris, Wim; (CA).
LIN, Yih-Shyan; (CA)
Agent: ROCHON, Marie-Hélène; Norton Rose Canada LLP/S.E.N.C.R.L., s.r.l. Suite 2500 1 place Ville-Marie Montréal, Québec H3B 1R1 (CA)
Priority Data:
61/349,442 28.05.2010 US
61/487,323 18.05.2011 US
Title (EN) HETEROCYCLYL-PYRIDINYL-BASED BIPHOSPHONIC ACID, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, COMPOSITION THEREOF AND METHOD OF USE THEREOF
(FR) ACIDE HÉTÉROCYCLYLE-PYRIDINYLE BISPHOSPHONIQUE, SEL PHARMACEUTIQUEMENT ACCEPTABLE DE CELUI-CI, COMPOSITION EN CONTENANT ET SON PROCÉDÉ D'UTILISATION
Abstract: front page image
(EN)The present invention relates to novel compounds, compositions containing said compounds and methods for inhibiting human farnesyl pyrophosphate synthase or for the treatment or prevention of disease conditions using said compounds, which may also be useful in the inhibition of FPPS enzymes of microorganisms and protozoan parasites such as the groups of Leishmania, Plasmodium, Trypanosoma, Toxoplasma and Cryptosporidium.
(FR)La présente invention concerne des composés inédits, des compositions contenant lesdits composés, des méthodes d'inhibition de la farnesyl-pyrophosphate synthase humaine ou des méthodes de traitement ou de prévention d'états pathologiques au moyen desdits composés, qui peuvent également s'avérer utiles en vue de l'inhibition des enzymes FPPS des microorganismes et des protozoaires parasites tels que ceux appartenant aux genres Leishmania, Plasmodium, Trypanosoma, Toxoplasma et Cryptosporidium.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)