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Machine translation
1. (WO2011147034) PROSTAGLANDIN-BISPHOSPHONATE CONJUGATE COMPOUNDS, METHODS OF MAKING SAME, AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/147034    International Application No.:    PCT/CA2011/000633
Publication Date: 01.12.2011 International Filing Date: 30.05.2011
IPC:
C07F 9/6558 (2006.01), A61K 31/675 (2006.01), A61K 47/48 (2006.01), A61P 19/08 (2006.01), C07F 9/547 (2006.01)
Applicants: SIMON FRASER UNIVERSITY [CA/CA]; Innovation Office 8888 University Drive Multi Tenant Facility Burnaby, British Columbia V5A 4W9 (CA) (For All Designated States Except US).
YOUNG, Robert N. [CA/CA]; (CA) (For US Only).
ARNS, Stephen [CA/CA]; (CA) (For US Only).
MOREAU, Anne [FR/CA]; (CA) (For US Only).
MORSHAD, Monzur [CA/CA]; (CA) (For US Only).
GIBE, Romelo [PH/SG]; (SG) (For US Only)
Inventors: YOUNG, Robert N.; (CA).
ARNS, Stephen; (CA).
MOREAU, Anne; (CA).
MORSHAD, Monzur; (CA).
GIBE, Romelo; (SG)
Agent: CHATTERJEE, Alakananda; Borden Ladner Gervais LLP 1200 Waterfront Centre 200 Burrard Street P.O. Box 48600 Vancouver, British Columbia V7X 1T2 (CA)
Priority Data:
61/349,694 28.05.2010 US
2,738,045 21.04.2011 CA
Title (EN) PROSTAGLANDIN-BISPHOSPHONATE CONJUGATE COMPOUNDS, METHODS OF MAKING SAME, AND USES THEREOF
(FR) COMPOSÉS CONJUGUÉS PROSTAGLANDINE-BISPHOSPHONATE, LEURS MÉTHODES DE FABRICATION ET LEURS UTILISATIONS
Abstract: front page image
(EN)The invention provides, in part, amino-bisphosphonate-prostaglandin conjugate compounds as well as methods for their synthesis. Said compounds may be used as EP4 agonist compounds in the prevention or treatment of conditions associated with abnormal or excessive bone loss, with abnormal or reduced bone resorption, or with abnormal calcium metabolism.
(FR)La présente invention concerne pour partie des composés conjugués amino-bisphosphonate-prostaglandine ainsi que leurs méthodes de synthèse. De tels composés peuvent être employés en tant qu'agonistes d'EP4 dans le traitement prophylactique ou thérapeutique d'états pathologiques associés à une perte osseuse anormale ou excessive, à une résorption osseuse anormale ou excessive ou à un métabolisme du calcium anormal.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)