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1. (WO2011146401) NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/146401    International Application No.:    PCT/US2011/036671
Publication Date: 24.11.2011 International Filing Date: 16.05.2011
IPC:
C07D 403/04 (2006.01), A61K 31/506 (2006.01), C07D 403/14 (2006.01), A61K 31/4025 (2006.01), A61K 31/517 (2006.01), C07D 405/14 (2006.01), A61K 31/4178 (2006.01), A61K 31/519 (2006.01), C07D 407/14 (2006.01), A61K 31/4184 (2006.01), A61K 31/55 (2006.01), C07D 409/14 (2006.01), A61K 31/423 (2006.01), A61K 31/558 (2006.01), C07D 413/14 (2006.01), A61K 31/428 (2006.01), A61K 31/5585 (2006.01), C07D 417/14 (2006.01), A61K 31/4365 (2006.01), A61P 31/14 (2006.01), C07D 471/04 (2006.01), A61K 31/437 (2006.01), C07D 207/16 (2006.01), C07D 487/04 (2006.01), A61K 31/439 (2006.01), C07D 401/12 (2006.01), C07D 495/04 (2006.01), A61K 31/4985 (2006.01), C07D 403/12 (2006.01), C07D 513/04 (2006.01), C07D 401/14 (2006.01)
Applicants: INTERMUNE, INC. [US/US]; 3280 Bayshore Boulevard Brisbane, CA 94005 (US) (For All Designated States Except US).
BUCKMAN, Brad [US/US]; (US) (For US Only).
NICHOLAS, John, B. [US/US]; (US) (For US Only).
SEREBRYANY, Vladimir [US/US]; (US) (For US Only).
SEIWERT, Scott, D. [US/US]; (US) (For US Only)
Inventors: BUCKMAN, Brad; (US).
NICHOLAS, John, B.; (US).
SEREBRYANY, Vladimir; (US).
SEIWERT, Scott, D.; (US)
Agent: HART, Daniel; Knobbe Martens Olson & Bear LLP 2040 Main Street 14th Floor Irvine, CA 92614 (US)
Priority Data:
61/361,328 02.07.2010 US
61/354,671 14.06.2010 US
61/425,718 21.12.2010 US
61/382,872 14.09.2010 US
61/405,138 20.10.2010 US
61/345,222 17.05.2010 US
61/345,553 17.05.2010 US
61/454,438 18.03.2011 US
Title (EN) NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION
(FR) NOUVEAUX INHIBITEURS DE LA RÉPLICATION DU VIRUS DE L'HÉPATITE C
Abstract: front page image
(EN)The embodiments provide compounds of the general Formulae (VI), (VII), (VIII), (IX), (X), (XI), (XII), (XIII), (XIV), and (XV) as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.
(FR)La présente invention concerne des composés de formule générale VI, VII, VIII, IX, X, XI, XII, XIII, XIV ou XV ainsi que des compositions, y compris des compositions pharmaceutiques, comprenant un composé sujet. L'invention a en outre pour objet des méthodes de traitement d'une infection par le virus de l'hépatite C et des méthodes de traitement de la fibrose du foie, lesdites méthodes impliquant de manière générale l'administration à un individu en ayant besoin d'une quantité efficace d'un composé sujet ou d'une composition sujette.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)