WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2011146300) NOVEL PROLYLCARBOXYPEPTIDASE INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/146300    International Application No.:    PCT/US2011/036161
Publication Date: 24.11.2011 International Filing Date: 12.05.2011
IPC:
C07D 235/02 (2006.01)
Applicants: MERCK SHARP & DOHME CORP. [US/US]; 126 East Lincoln Avenue Rahway, New Jersey 07065-0907 (US) (For All Designated States Except US).
DEBENHAM, John, S. [US/US]; (US) (For US Only).
SHEN, Dong-Ming [US/US]; (US) (For US Only).
GRAHAM, Thomas, H. [US/US]; (US) (For US Only).
CLEMENTS, Matthew, J. [US/US]; (US) (For US Only).
ZHANG, Yong [US/US]; (US) (For US Only)
Inventors: DEBENHAM, John, S.; (US).
SHEN, Dong-Ming; (US).
GRAHAM, Thomas, H.; (US).
CLEMENTS, Matthew, J.; (US).
ZHANG, Yong; (US)
Common
Representative:
MERCK SHARP & DOHME CORP.; 126 East Lincoln Avenue Rahway, New Jersey 07065-0907 (US)
Priority Data:
61/345,303 17.05.2010 US
Title (EN) NOVEL PROLYLCARBOXYPEPTIDASE INHIBITORS
(FR) NOUVEAUX INHIBITEURS DE PROLYLCARBOXYPEPTIDASE
Abstract: front page image
(EN)Compounds of structural formula I are inhibitors of prolylcarboxypeptidase (PrCP). The compounds of the present invention are useful for the prevention and treatment of conditions related to the enzymatic activity of PrCP such as abnormal metabolism, including obesity; diabetes; metabolic syndrome; obesity related disorders; and diabetes related disorders.
(FR)La présente invention concerne des composés de formule structurale I qui sont des inhibiteurs de prolylcarboxypeptidase (PrCP). Les composés de la présente invention sont utiles pour la prévention et le traitement d'affections associées à l'activité enzymatique de PrCP telles qu'un métabolisme anormal, comprenant l'obésité; le diabète; le syndrome métabolique; les troubles associés à l'obésité; et les troubles associés au diabète.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)