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1. (WO2011145744) ANTI-HUMAN TROP-2 ANTIBODY HAVING ANTITUMOR ACTIVITY IN VIVO
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/145744    International Application No.:    PCT/JP2011/061709
Publication Date: 24.11.2011 International Filing Date: 17.05.2011
IPC:
C07K 16/32 (2006.01), A61K 39/395 (2006.01), A61K 45/00 (2006.01), A61P 35/00 (2006.01), C12N 5/10 (2006.01), C12N 15/09 (2006.01), G01N 33/574 (2006.01), C12P 21/08 (2006.01)
Applicants: LIVTECH, INC. [JP/JP]; Teikyo University Biotechnology Research Center 1F, 907, Nogawa, Miyamae-ku, Kawasaki-shi, Kanagawa 2160001 (JP) (For All Designated States Except US).
NAKAMURA, Koji [JP/JP]; (JP) (For US Only).
OKAMURA, Kentaro [JP/JP]; (JP) (For US Only).
TAMURA, Maki [JP/JP]; (JP) (For US Only).
YANAI, Hiroyuki [JP/JP]; (JP) (For US Only).
KANKE, Toru [JP/JP]; (JP) (For US Only)
Inventors: NAKAMURA, Koji; (JP).
OKAMURA, Kentaro; (JP).
TAMURA, Maki; (JP).
YANAI, Hiroyuki; (JP).
KANKE, Toru; (JP)
Agent: KOBAYASHI, Hiroshi; ABE, IKUBO & KATAYAMA, Fukuoka Bldg. 9th Fl., 8-7, Yaesu 2-chome, Chuo-ku, Tokyo 1040028 (JP)
Priority Data:
2010-113302 17.05.2010 JP
Title (EN) ANTI-HUMAN TROP-2 ANTIBODY HAVING ANTITUMOR ACTIVITY IN VIVO
(FR) ANTICORPS ANTI-TROP-2 HUMAIN AYANT UNE ACTIVITÉ ANTICANCÉREUSE IN VIVO
(JA) in vivoで抗腫瘍活性を有する抗ヒトTROP-2抗体
Abstract: front page image
(EN)Provided are: an antibody which reacts specifically with hTROP-2 and has an antitumor activity in vivo; a hybridoma producing said antibody; a complex of said antibody with a drug; a medicinal composition for the diagnosis or treatment of tumor; a method for detecting tumor; and a kit for the detection or diagnosis of tumor.
(FR)La présente invention concerne : un anticorps qui réagit spécifiquement avec hTROP-2 et a une activité anticancéreuse in vivo ; un hybridome produisant ledit anticorps ; un complexe dudit anticorps avec un médicament ; une composition médicinale pour le diagnostic ou le traitement d'une tumeur ; un procédé pour détecter une tumeur ; et un kit pour la détection ou le diagnostic d'une tumeur.
(JA) 本発明は、hTROP-2と特異的に反応しin vivoで抗腫瘍活性を有する抗体、当該抗体を産生するハイブリドーマ、当該抗体と薬剤との複合体、腫瘍の診断用又は治療用医薬組成物、腫瘍の検出方法、腫瘍の検出用又は診断用キットを提供する。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)