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Machine translation
1. (WO2011144999) PLASMA PROTEIN-A2 (PAPP-A2) AS A MARKER FOR DETECTING RISK OF CHROMOSOMAL ABNORMALITIES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/144999    International Application No.:    PCT/IB2011/001146
Publication Date: 24.11.2011 International Filing Date: 25.05.2011
IPC:
G01N 33/68 (2006.01)
Applicants: REZNIK, Sandra [US/US]; (US).
GROSS, Susan [US/US]; (US)
Inventors: REZNIK, Sandra; (US).
GROSS, Susan; (US)
Common
Representative:
REZNIK, Sandra [US/US]; 7 Dante St. Larchmont, NY 10538-1608 (US)
Priority Data:
61/359,568 17.05.2010 US
Title (EN) PLASMA PROTEIN-A2 (PAPP-A2) AS A MARKER FOR DETECTING RISK OF CHROMOSOMAL ABNORMALITIES
(FR) PROTÉINE PLASMATIQUE A2 (PAPP-A2) COMME MARQUEUR DE DÉTECTION D'UN RISQUE D'ANOMALIES CHROMOSOMIQUES
Abstract: front page image
(EN)The subject invention is directed to the detection of increased risk of a chromosomal abnormality through assay of maternal serum PAPP-A2. Chromosomal abnormality includes any chromosomal disorder where there is alteration of structure and/or number of the normal chromosome complement. Provided are methods of determining whether a pregnant woman is at elevated risk for carrying a fetus with a chromosomal abnormality. Also provided are assays and kits for determining whether a pregnant woman is at elevated risk for carrying a fetus with a chromosomal abnormality.
(FR)La présente invention concerne la détection d'un risque accru d'une anomalie chromosomique par le test de PAPP-A2 dans le sérum maternel. L'anomalie chromosomique comprend tout trouble chromosomique dans lequel il y a une altération de la structure et/ou du nombre du complément chromosomique normal. L'invention concerne des procédés permettant de déterminer si une femme enceinte présente un risque élevé de porter un fœtus affecté d'une anomalie chromosomique. L'invention concerne également des tests et des kits pour déterminer si une femme enceinte présente un risque élevé de porter un fœtus affecté d'une anomalie chromosomique.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)