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1. (WO2011143553) COMPOSITIONS AND METHODS FOR TARGETING A3G:RNA COMPLEXES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/143553    International Application No.:    PCT/US2011/036430
Publication Date: 17.11.2011 International Filing Date: 13.05.2011
IPC:
C12Q 1/68 (2006.01), C40B 30/04 (2006.01), C40B 40/06 (2006.01)
Applicants: UNIVERSITY OF ROCHESTER [US/US]; 601 Elmwood Avenue, Box OTT Rochester, NY 14642 (US) (For All Designated States Except US).
SMITH, Harold, C. [US/US]; (US) (For US Only).
PROHASKA, Kimberly [US/US]; (US) (For US Only).
MCDOUGALL, William, M. [US/US]; (US) (For US Only)
Inventors: SMITH, Harold, C.; (US).
PROHASKA, Kimberly; (US).
MCDOUGALL, William, M.; (US)
Agent: NGUYEN, Quang, D.; Riverside Law, LLP 300 Four Falls Corporate Center, Suite 710 300 Conshohocken State Road West Conshohocken, PA 19428 (US)
Priority Data:
61/334,902 14.05.2010 US
Title (EN) COMPOSITIONS AND METHODS FOR TARGETING A3G:RNA COMPLEXES
(FR) COMPOSITIONS ET PROCÉDÉS POUR CIBLER DES COMPLEXES A3G:ARN
Abstract: front page image
(EN)The present invention provides an assay for screening any agent that modulates the ability of A3G to bind with RNA. The invention provides an agent identified by high throughput screening methods and methods of treatment using the identified agent as a means of inhibiting HIV infection and reducing the emergence of viral drug-resistance.
(FR)La présente invention propose un dosage pour filtrer n'importe quel agent qui module la capacité de l'A3G à se lier à de l'ARN. L'invention propose un agent identifié par des procédés de filtration à haute productivité et des procédés de traitement utilisant l'agent identifié en tant que moyen pour empêcher une infection HIV et réduire l'émergence d'une résistance aux médicaments antiviraux.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)