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Machine translation
1. (WO2011143521) ENHANCED HOMING AND ENGRAFTMENT OF HEMATOPOIETIC STEM CELLS USING CD26 INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/143521    International Application No.:    PCT/US2011/036380
Publication Date: 17.11.2011 International Filing Date: 13.05.2011
IPC:
C12N 5/0789 (2010.01), C07D 207/08 (2006.01), C07D 207/06 (2006.01), C12N 5/077 (2010.01), C12N 5/02 (2006.01), A61K 35/28 (2006.01)
Applicants: DARA BIOSCIENCES, INC. [US/US]; 8601 Six Forks Road, Suite 160 Raleigh, North Carolina 27615 (US) (For All Designated States Except US).
SEVERYNSE-STEVENS, Diana [US/US]; (US) (For US Only).
DIDSBURY, John R. [US/US]; (US) (For US Only)
Inventors: SEVERYNSE-STEVENS, Diana; (US).
DIDSBURY, John R.; (US)
Agent: MYERS BIGEL SIBLEY & SAJOVEC, P.A.; P.O. Box 37428 Raleigh, North Carolina 27627 (US)
Priority Data:
61/334,289 13.05.2010 US
Title (EN) ENHANCED HOMING AND ENGRAFTMENT OF HEMATOPOIETIC STEM CELLS USING CD26 INHIBITORS
(FR) ECOTROPISME ET PRISE DE GREFFE AMÉLIORÉS DE CELLULES SOUCHES HÉMATOPOÏÉTIQUES GRÂCE À DES INHIBITEURS DE CD26
Abstract: front page image
(EN)The present invention relates to methods for improving the therapeutic usefulness of hematopoietic stem cells (HSC). Specifically, the invention involves contacting HSC with compounds of the invention to enhance homing and/or engraftment to bone marrow and HSC thus contacted.
(FR)La présente invention concerne des procédés d'amélioration de l'utilité thérapeutique de cellules souches hématopoïétiques (CSH). L'invention implique, plus précisément, la mise en contact de CSH avec des composés de l'invention afin de favoriser l'écotropisme et/ou la prise de greffe à l'égard de la moelle osseuse des CSH ainsi traitées.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)