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1. (WO2011143459) PYRROLOPYRIDINE AND PYRROLOPYRIMIDINE INHIBITORS OF KINASES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/143459    International Application No.:    PCT/US2011/036298
Publication Date: 17.11.2011 International Filing Date: 12.05.2011
IPC:
C07D 471/04 (2006.01), C07D 487/04 (2006.01), A61K 31/437 (2006.01), A61K 31/519 (2006.01), A61P 35/00 (2006.01)
Applicants: ABBVIE INC. [US/US]; 1 North Waukegan Road North Chicago, IL 60064 (US) (For All Designated States Except US).
MICHAELIDES, Michael [US/US]; (US) (For US Only).
JUDD, Andrew [US/US]; (US) (For US Only).
FIX-STENZEL, Shannon [US/US]; (US) (For US Only)
Inventors: MICHAELIDES, Michael; (US).
JUDD, Andrew; (US).
FIX-STENZEL, Shannon; (US)
Agent: STEELE, Susan, L.; Abbott Laboratories 100 Abbott Park Road AP6A-1/D0377 Abbott Park, IL 60064 (US)
Priority Data:
61/333,850 12.05.2010 US
Title (EN) PYRROLOPYRIDINE AND PYRROLOPYRIMIDINE INHIBITORS OF KINASES
(FR) PYRROLOPYRIDINE ET PYRROLOPYRIMIDINE INHIBITRICES DE KINASES
Abstract: front page image
(EN)The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts, wherein A, B, R1, R2, R3, R4a, R5, and Z are defined in the description. The present invention relates also to methods of making said compounds, and compositions containing said compounds which are useful for inhibiting kinases such as aurora.
(FR)La présente invention concerne des composés de formule (I) ou des sels pharmaceutiquement acceptables, A, B, R1, R2, R3, R4a, R5, et Z étant tels que définis dans la description. La présente invention concerne également des procédés de fabrication desdits composés, et des compositions contenant lesdits composés qui sont utiles pour l'inhibition de kinases telles qu'aurora.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)