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1. (WO2011143187) LACTOFERRIN -BASED BIOMATERIALS FOR TISSUE REGENERATION AND DRUG DELIVERY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/143187    International Application No.:    PCT/US2011/035881
Publication Date: 17.11.2011 International Filing Date: 10.05.2011
IPC:
A61K 38/40 (2006.01), A61K 38/16 (2006.01), A61K 9/06 (2006.01), A61P 19/00 (2006.01), A61P 21/00 (2006.01)
Applicants: UNIVERSITY OF CONNECTICUT [US/US]; 263 Farmington Avenue Farmington, CT 06030-6207 (US) (For All Designated States Except US).
SREEDHARAN NAIR, Lakshmi [IN/US]; (US) (For US Only)
Inventors: SREEDHARAN NAIR, Lakshmi; (US)
Agent: BROOK, David, E.; Hamilton, Brook, Smith & Reynolds, P.C. 530 Virginia Rd, P.o. Box 9133 Concord, MA 01742-9133 (US)
Priority Data:
61/332,935 10.05.2010 US
Title (EN) LACTOFERRIN -BASED BIOMATERIALS FOR TISSUE REGENERATION AND DRUG DELIVERY
(FR) BIOMATÉRIAUX À BASE DE LACTOFERRINE POUR LA RÉGÉNÉRATION TISSULAIRE ET LA DÉLIVRANCE DE MÉDICAMENTS
Abstract: front page image
(EN)The invention provides biomatrix compositions comprising cross-linked lactoferrin, either alone or in combination with other organic or inorganic components. Also provided are methods of making and using the biomatrix compositions. As described herein, cross-linked lactoferrin biomatrix retains the bioactivities of the lactoferrin molecule. The biomatrix composition can act as a matrix for cell adhesion and growth and is particularly useful in musculoskeletal tissue regeneration. The biomatrix compositions can be pre-formed or injectable and can act as a cell, drug or protein delivery vehicle.
(FR)L'invention concerne des compositions de biomatrices comprenant de la lactoferrine réticulée, seule ou combinée à d'autres composants organiques ou inorganiques. L'invention concerne également des procédés de fabrication et d'utilisation des compositions de biomatrices. Les biomatrices de lactoferrine réticulée ci-décrites conservent la bioactivité de la molécule de lactoferrine. Les compositions de biomatrices peuvent agir comme matrice pour l'adhésion et la croissance cellulaire, et sont particulièrement utiles dans la régénération du tissu musculosquelettique. Les compositions de biomatrices peuvent être préformées ou injectables, et peuvent agir comme véhicule de délivrance d'une cellule, d'un médicament ou d'une protéine.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)